Description

4-Cyanobenzyl Phosphonic Acid is a high-purity, bifunctional organic intermediate of significant importance in advanced chemical synthesis. Its unique structure, featuring both a phosphonic acid group and a cyano-substituted aromatic ring, makes it a versatile building block for creating complex molecules. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and materials science industries seeking to develop novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly those targeting bone-related disorders (osteoporosis) or requiring phosphonate-based bioisosteres.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, plant growth regulators, and pesticides with enhanced activity and environmental profiles.
• Ligand and Catalyst Design: Serves as a chelating agent or precursor for metal-organic frameworks (MOFs) and homogeneous catalysis due to its phosphonic acid functionality.
• Surface Modification Agent: Employed to functionalize metal oxides (e.g., titanium, aluminum) and other surfaces to improve adhesion, corrosion resistance, or biocompatibility in coatings and composites.
• Polymer Additive & Monomer: Acts as a flame retardant precursor or a cross-linking agent in specialty polymers and resins.
• Chemical Research & Development: A valuable reagent in organic and medicinal chemistry for constructing complex molecular architectures.

Basic Information

Product Name	4-Cyanobenzyl Phosphonic Acid
CAS No.	75001-24-0
Molecular Formula	C8H8NO3P
Molecular Weight	197.13 g/mol
Synonyms	(4-Cyanophenyl)methylphosphonic Acid; p-Cyanobenzylphosphonic Acid; 4-(Phosphonomethyl)benzonitrile; Benzonitrile, 4-(phosphonomethyl)-; Phosphonic acid, P-[(4-cyanophenyl)methyl]-; (4-Cyanobenzyl)phosphonic acid
EINECS	Contact for details

Quality Control

Our 4-Cyanobenzyl Phosphonic Acid is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing to ensure it meets stringent purity and consistency standards. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming specifications for identity, assay, and impurity profiles. We support cGMP and ISO standards for pharmaceutical and industrial applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Melting Point	Contact for details
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.