Description

A,A'-Dibromo-p-Xylene-D8 is a deuterated isotopologue of a key bifunctional alkylating agent, where the aromatic methylene hydrogens are replaced with deuterium atoms. This deuteration makes it an invaluable internal standard and tracer in advanced analytical chemistry, particularly for mass spectrometry, ensuring superior accuracy and reliability in quantitative analysis. It is essential for researchers and manufacturers in the fields of pharmaceutical development, agrochemical research, and advanced material science who require precise isotopic labeling for kinetic studies, metabolic pathway tracing, and method validation.

Application

• Internal Standard for Mass Spectrometry (MS): Serves as a critical, non-interfering reference compound in GC-MS and LC-MS analysis for the quantification of its non-deuterated analogue and related compounds.
• Pharmaceutical Research & Development: Used as a deuterated tracer in drug metabolism and pharmacokinetics (DMPK) studies to investigate metabolic pathways and stability.
• Agrochemical Analysis: Employed in environmental and residue analysis to accurately measure levels of pesticides or their degradation products that share a similar xylene-based structure.
• Organic Synthesis Intermediate: Functions as a deuterium-labeled building block for the synthesis of more complex deuterated molecules for research purposes.
• NMR Spectroscopy: Useful as a solvent or reagent in nuclear magnetic resonance studies where deuterated compounds are required.
• Material Science Research: Acts as a precursor for creating deuterated polymers or porous organic frameworks for specialized material properties studies.

Basic Information

Product Name	A,A'-Dibromo-p-Xylene-D8
CAS No.	74903-77-8
Molecular Formula	C8D8Br2
Molecular Weight	279.98 g/mol
Synonyms	1,4-Bis(bromomethyl)-2,3,5,6-tetradeuteriobenzene; α,α'-Dibromo-p-xylene-d8; p-Xylylene-d8 dibromide; Deutero-p-xylylene dibromide; 2,3,5,6-Tetradeutero-1,4-bis(bromomethyl)benzene; D8-α,α'-Dibromo-p-xylene; p-Bis(bromomethyl)benzene-d8
EINECS	Contact for details

Quality Control

Every batch of A,A'-Dibromo-p-Xylene-D8 is manufactured and analyzed under strict quality protocols to ensure high isotopic purity and chemical integrity, critical for its use as an analytical standard. Our quality assurance includes comprehensive testing via NMR, HPLC, and mass spectrometry to confirm deuterium enrichment and chemical purity. Certificates of Analysis (COA) detailing lot-specific results are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. Due to its light-sensitive nature, handling and storage should minimize exposure to direct light.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Deuterium Enrichment (NMR)	≥ 98 atom % D
Purity (HPLC)	≥ 97%
Melting Point	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.