Description

1,4-Di(Bromomethyl)Benzene-D4 is a deuterated analog of 1,4-bis(bromomethyl)benzene, a valuable building block in organic synthesis and materials science. This compound is specifically designed for applications requiring isotopic labeling, offering enhanced stability and traceability in research and development. It is essential for scientists and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require high-purity, isotopically labeled intermediates for mechanistic studies, metabolic research, and the development of novel polymers and liquid crystals.

Application

• Pharmaceutical Research & Development: As a deuterium-labeled intermediate for the synthesis of isotopically labeled drug candidates, enabling pharmacokinetic (PK) and metabolic stability studies.
• Agrochemical Synthesis: Used in creating labeled analogs of pesticides and herbicides for environmental fate and metabolic pathway analysis.
• Polymer & Materials Science: A key monomer for synthesizing deuterated polymers, such as poly(p-phenylene vinylene) (PPV) derivatives, for specialized optical and electronic applications.
• Liquid Crystal Manufacturing: Serves as a precursor for deuterated liquid crystal compounds used in high-performance displays (e.g., LCDs) to modify physical properties.
• Organic Synthesis & Catalysis: Acts as a versatile alkylating agent in cross-coupling reactions and for introducing the p-xylylene moiety in complex molecule construction.
• Analytical Standards & Metabolite Identification: Employed as an internal standard in mass spectrometry (MS) and nuclear magnetic resonance (NMR) spectroscopy for accurate quantification.

Basic Information

Product Name	1,4-Di(Bromomethyl)Benzene-D4
CAS No.	74903-75-6
Molecular Formula	C8D4H4Br2
Molecular Weight	277.96 g/mol
Synonyms	p-Xylylene Dibromide-d4; 1,4-Bis(bromomethyl)benzene-d4; α,α'-Dibromo-p-xylene-d4; p-Bis(bromomethyl)benzene-d4; Deuteron p-Xylylene Dibromide; [D4]-1,4-Bis(bromomethyl)benzene; p-(Dibromomethyl)benzene-d4; Tetradeutero-1,4-bis(bromomethyl)benzene
EINECS	Contact for details

Quality Control

Our 1,4-Di(Bromomethyl)Benzene-D4 is manufactured under strict quality control protocols to ensure high chemical and isotopic purity. Each batch is analyzed using advanced techniques including NMR, HPLC, and GC-MS to confirm identity, assay, and deuterium enrichment. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We adhere to cGMP principles where applicable to support our clients in regulated research environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, handling should be performed under subdued light or in amber glass containers to prevent decomposition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Deuterium Enrichment (NMR/MS)	≥ 98 atom % D
Melting Point	142 - 146 °C

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.