Description

3-(2-Amino-Ethyl)-1H-Indole-5-Carboxylic Acid is a versatile indole derivative that serves as a critical building block in advanced organic synthesis. Its bifunctional structure, featuring both a carboxylic acid and a primary amine group, makes it a valuable precursor for constructing complex heterocyclic systems and pharmacologically active molecules. This compound is essential for research and development chemists in the pharmaceutical, agrochemical, and fine chemical industries seeking to develop new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of tryptamine-based drug candidates, including potential serotonin receptor modulators and central nervous system (CNS) active compounds.
• Agrochemical Research: Used in the development of novel plant growth regulators and pesticides that leverage the indole scaffold for biological activity.
• Bioconjugation & Probe Synthesis: The amine and carboxylic acid groups facilitate its use in creating fluorescent probes, affinity labels, and other biochemical tools for life science research.
• Peptidomimetics & Medicinal Chemistry: Employed as a constrained amino acid analog to introduce the indole moiety into peptide chains, modifying their stability, conformation, and receptor binding properties.
• Material Science Precursor: Acts as a monomer or functionalizing agent in the synthesis of specialty polymers and organic electronic materials.

Basic Information

Product Name	3-(2-Amino-Ethyl)-1H-Indole-5-Carboxylic Acid
CAS No.	74884-75-6
Molecular Formula	C11H12N2O2
Molecular Weight	204.23 g/mol
Synonyms	5-Carboxytryptamine; 5-CT; 5-Carboxy-3-(2-aminoethyl)indole; 3-(2-Aminoethyl)-1H-indole-5-carboxylic acid; 5-Carboxyindole-3-ethylamine; 1H-Indole-5-carboxylic acid, 3-(2-aminoethyl)-; 5-Carboxytryptamine hydrochloride (salt form); 5-CT free base
EINECS	Contact for details

Quality Control

Our 3-(2-Amino-Ethyl)-1H-Indole-5-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. For long-term storage, consider using a desiccant.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.