Description

Phenyl-D5 Isothiocyanate is a deuterated isotopologue of phenyl isothiocyanate, where five hydrogen atoms on the phenyl ring are replaced with deuterium. This compound is a critical stable isotope-labeled reagent, primarily used as an internal standard in quantitative mass spectrometry to ensure analytical accuracy and reliability. It is essential for researchers and quality control laboratories in the pharmaceutical, agrochemical, and analytical chemistry sectors who require precise quantification of metabolites, impurities, or degradation products.

Application

• Internal Standard for LC-MS/MS and GC-MS analysis in bioanalytical and pharmacokinetic studies.
• Stable isotope-labeled precursor for synthesizing deuterated pharmaceutical intermediates and metabolites.
• Derivatization agent in Edman degradation for protein sequencing, using the deuterated form for method development and validation.
• Chemical probe in reaction mechanism studies utilizing Isotope Effects.
• Critical reagent in environmental testing for tracing and quantifying specific chemical pollutants.
• Use in the synthesis of labeled compounds for use as NMR or MS standards in academic and industrial research.

Basic Information

Product Name	Phenyl-D5 Isothiocyanate
CAS No.	74881-77-9
Molecular Formula	C7D5NS
Molecular Weight	141.21 g/mol
Synonyms	Deuterated Phenyl Isothiocyanate; Phenyl-d5 isothiocyanate; (2,3,4,5,6-Pentadeuteriophenyl) isothiocyanate; Isothiocyanic Acid Pentadeuteriophenyl Ester; PITC-d5; C6D5NCS; Phenyl Isothiocyanate-d5
EINECS	Contact for details

Quality Control

Our Phenyl-D5 Isothiocyanate is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including NMR, HPLC, and mass spectrometry, to confirm chemical identity, isotopic purity (D-enrichment), and chemical purity. A detailed Certificate of Analysis (COA) is provided with each shipment, ensuring traceability and compliance with your research and development protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (MS)	Conforms to structure
Purity (HPLC)	≥98.0%
Isotopic Purity (D-enrichment)	≥98 atom % D
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.