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1-O,3-O:2-O,4-o-Bis(Phenylmethylene)-D-Glucitol 5,6-Diacetate CAS NO 74842-25-4


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CAS No.:74842-25-4

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

1-O,3-O:2-O,4-o-Bis(Phenylmethylene)-D-Glucitol 5,6-Diacetate is a specialized carbohydrate derivative, a protected form of D-glucitol, which serves as a crucial chiral intermediate and protecting group reagent in advanced organic synthesis. Its value lies in enabling precise stereochemical control and selective functionalization in the construction of complex molecules. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries who require high-purity building blocks for developing active ingredients and novel materials.

Application

  • Pharmaceutical Intermediate: A key chiral synthon for the synthesis of nucleoside analogs, antiviral agents, and other active pharmaceutical ingredients (APIs) requiring specific sugar moiety modifications.
  • Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides where the glucitol scaffold imparts desired biological activity or selectivity.
  • Fine Chemical Production: Serves as a versatile building block for creating specialty chemicals, ligands for catalysis, and advanced materials with tailored properties.
  • Carbohydrate Chemistry Research: An important tool for academic and industrial R&D in glycoscience, used to study glycosylation reactions, enzyme inhibitors, and carbohydrate-based polymers.
  • Protecting Group Strategy: The bis(phenylmethylene) and acetate groups provide orthogonal protection for hydroxyl functions, allowing for sequential, selective deprotection in multi-step synthetic routes.

Basic Information

Item Detail
Product Name 1-O,3-O:2-O,4-o-Bis(Phenylmethylene)-D-Glucitol 5,6-Diacetate
CAS No. 74842-25-4
Molecular Formula C24H26O8
Molecular Weight 442.46 g/mol
Synonyms 1,3:2,4-Di-O-benzylidene-D-glucitol 5,6-diacetate; D-Glucitol, 1,3:2,4-bis-O-(phenylmethylene)-, 5,6-diacetate; 1,3:2,4-Di-O-benzylidene-D-sorbitol 5,6-diacetate; 5,6-Di-O-acetyl-1,3:2,4-di-O-benzylidene-D-glucitol; D-Glucitol Diacetate Dibenzylidene Acetal; 1,3:2,4-Bis-O-(phenylmethylene)-D-glucitol 5,6-diacetate
EINECS Contact for details

Quality Control

Our 1-O,3-O:2-O,4-o-Bis(Phenylmethylene)-D-Glucitol 5,6-Diacetate is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and chiral analysis to ensure stereochemical integrity. We provide a detailed Certificate of Analysis (COA) with every shipment, documenting all critical parameters to support your regulatory and R&D requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). The compound should be kept under an inert atmosphere for long-term storage to maintain stability.

Specification

Item Specification
Appearance White to off-white crystalline powder
Identification (IR) Conforms to structure
Identification (NMR) Conforms to structure
Purity (HPLC) ≥ 98.0%
Specific Rotation Contact for details
Loss on Drying ≤ 0.5%
Residue on Ignition ≤ 0.1%
Heavy Metals ≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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