Description

5,6-Dihydro-1,3-Bis(trimethylsilyl)-2,4(1H,3H)-pyrimidinedione is a specialized organosilicon-protected pyrimidine derivative of significant interest in advanced organic synthesis. This compound matters as a versatile and reactive building block, offering chemists a protected nucleobase scaffold for constructing complex molecules with precision. It is primarily needed by research institutions and pharmaceutical companies engaged in nucleoside chemistry, medicinal chemistry, and the development of novel agrochemicals and fine chemicals.

Application

• Nucleoside & Nucleotide Analog Synthesis: Serves as a key protected intermediate in the preparation of modified nucleosides for antiviral and anticancer drug discovery.
• Medicinal Chemistry Building Block: Used in the design and synthesis of heterocyclic libraries targeting various biological pathways.
• Agrochemical Research: Acts as a precursor in developing novel pesticides and herbicides with specific modes of action.
• Fine Chemical Production: Employed in the multi-step synthesis of complex, high-value specialty chemicals.
• Academic & Industrial R&D: A valuable reagent for methodological studies in organic synthesis, particularly involving silyl protection strategies.

Basic Information

Product Name	5,6-Dihydro-1,3-Bis(trimethylsilyl)-2,4(1H,3H)-pyrimidinedione
CAS No.	74810-47-2
Molecular Formula	C12H24N2O2Si2
Molecular Weight	284.50 g/mol
Synonyms	1,3-Bis(trimethylsilyl)-5,6-dihydrouracil; 5,6-Dihydro-1,3-bis(trimethylsilyl)uracil; 1,3-Bis-O-(trimethylsilyl)-5,6-dihydro-2,4-pyrimidinedione; Dihydro-1,3-bis(trimethylsilyl)uracil; 2,4(1H,3H)-Pyrimidinedione, 5,6-dihydro-1,3-bis(trimethylsilyl)-; TMS-protected dihydrouracil
EINECS	Contact for details

Quality Control

Our 5,6-Dihydro-1,3-Bis(trimethylsilyl)-2,4(1H,3H)-pyrimidinedione is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) detailing batch-specific results are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.