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.Beta.-D-Glucopyranosiduronic Acid, Phenyl 1-Thio-, Ethyl Ester, Triacetate CAS NO 74774-12-2


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CAS No.:74774-12-2

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

.Beta.-D-Glucopyranosiduronic Acid, Phenyl 1-Thio-, Ethyl Ester, Triacetate is a sophisticated thioglycoside derivative, serving as a crucial protected intermediate in synthetic carbohydrate chemistry. Its value lies in enabling the precise construction of complex glycoconjugates and oligosaccharides, where the thioglycoside moiety acts as a versatile glycosyl donor or acceptor. This compound is essential for researchers and manufacturers in the pharmaceutical and biotechnology sectors, particularly those developing novel glycotherapeutics, diagnostic probes, and enzyme inhibitors.

Application

  • Glycoconjugate Synthesis: A key protected building block for the chemical synthesis of complex oligosaccharides, glycopeptides, and glycolipids.
  • Pharmaceutical Intermediates: Used in the research and development of carbohydrate-based drugs, including antiviral agents, anti-inflammatory compounds, and targeted cancer therapies.
  • Enzyme Substrate & Inhibitor Development: Serves as a substrate or inhibitor precursor for glycosidase and glycosyltransferase enzymes, aiding in biochemical studies and drug discovery.
  • Chemical Biology Probes: Utilized to create labeled carbohydrate probes for studying carbohydrate-protein interactions, cell surface labeling, and metabolic pathway analysis.
  • Material Science Research: Potential intermediate for synthesizing functionalized polymers or surfaces with specific carbohydrate motifs for biosensing or biocompatibility applications.

Basic Information

Product Name .Beta.-D-Glucopyranosiduronic Acid, Phenyl 1-Thio-, Ethyl Ester, Triacetate
CAS No. 74774-12-2
Molecular Formula C₂₁H₂₆O₁₀S
Molecular Weight 470.49 g/mol
Synonyms Phenyl 1-Thio-β-D-glucopyranosiduronic Acid Ethyl Ester Triacetate; Ethyl (Phenyl 1-Thio-β-D-glucopyranosid)uronate Triacetate; 1-Thio-β-D-glucopyranosiduronic Acid, Phenyl-, Ethyl Ester, Triacetate; Phenyl 1-Thio-β-D-glucuronate Triacetate Ethyl Ester; Thioglycoside Donor Glucuronate Triacetate; β-D-Glucopyranosiduronic Acid, Phenyl 1-Thio-, Ethyl Ester, 2,3,4-Triacetate
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Quality Control

Our .Beta.-D-Glucopyranosiduronic Acid, Phenyl 1-Thio-, Ethyl Ester, Triacetate is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation by NMR and mass spectrometry, to ensure it meets the high standards required for research and development. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting critical specifications such as assay purity, chiral purity, and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider storing under an inert atmosphere.

Specification

Item Specification
Appearance White to off-white crystalline powder or solid
Identification (IR) Conforms to structure
Identification (NMR) Conforms to structure
Purity (HPLC) ≥ 97.0%
Chiral Purity ≥ 99.0% β-anomer
Water Content (KF) ≤ 0.5%
Residual Solvents (GC) Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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