Description

4-(Benzyloxy)-3-Methoxy-Benzyl Alcohol-D2 is a deuterated derivative of a benzyl-protected vanillyl alcohol, where two hydrogen atoms are replaced with deuterium. This deuteration is critical for enhancing metabolic stability and traceability in advanced research applications, making it a valuable tool for mechanistic studies. It is primarily utilized by researchers and developers in the pharmaceutical and agrochemical industries for use as a stable isotope-labeled intermediate in the synthesis of novel compounds and as an internal standard in analytical methods like LC-MS.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of deuterated drug candidates, particularly for neurological and metabolic targets.
• Metabolic Tracing: Used as a stable isotope-labeled probe in pharmacokinetic (PK) and absorption, distribution, metabolism, and excretion (ADME) studies.
• Analytical Standard: Employed as an internal standard in mass spectrometry (LC-MS, GC-MS) for the accurate quantification of its non-deuterated counterpart in complex matrices.
• Agrochemical Research: Acts as a precursor in the development of novel, labeled pesticides or herbicides for environmental fate studies.
• Chemical Biology: Utilized in probing enzyme mechanisms and biological pathways where isotopic labeling is required.
• Material Science Research: Investigated as a monomer or precursor for specialized polymers and advanced organic materials.

Basic Information

Product Name	4-(Benzyloxy)-3-Methoxy-Benzyl Alcohol-D2
CAS No.	74719-60-1
Molecular Formula	C15H14D2O3
Molecular Weight	244.31 g/mol
Synonyms	3-Methoxy-4-(phenylmethoxy)benzenemethanol-d2; Vanillyl Alcohol Benzyl Ether-d2; 4-(Benzyloxy)-3-methoxybenzyl-d2 Alcohol; 1-[4-(Benzyloxy)-3-methoxyphenyl]methanol-d2; Benzyl Vanillyl Ether-d2; Deuterated Benzyl Vanillyl Ether; (4-Benzyloxy-3-methoxy-phenyl)-methanol-d2
EINECS	Contact for details

Quality Control

Our 4-(Benzyloxy)-3-Methoxy-Benzyl Alcohol-D2 is manufactured under strict quality systems. Each batch undergoes comprehensive analytical testing, including NMR (¹H, ²H, ¹³C) for structural and isotopic purity confirmation, HPLC for chemical purity assessment, and mass spectrometry for identity verification. Certificates of Analysis (COA) detailing isotopic enrichment (D-atom %), chemical purity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity (D-atom %)	≥ 98.0% (by ²H NMR or MS)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.