Description

7-Chlorothieno[3,2-B]Pyridin-5(4H)-One is a high-value heterocyclic building block and key synthetic intermediate in advanced organic chemistry. This compound matters for its crucial role in the research and development of novel active pharmaceutical ingredients (APIs), particularly in medicinal chemistry programs targeting complex therapeutic areas. Pharmaceutical R&D laboratories, agrochemical innovators, and specialty chemical manufacturers need this precise intermediate to construct new molecular entities with potential biological activity.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly for central nervous system (CNS) and anti-infective agents.
• Medicinal Chemistry Research: Used as a versatile scaffold for constructing fused heterocyclic libraries in high-throughput screening and structure-activity relationship (SAR) studies.
• Agrochemical Development: Serves as a building block for creating new active ingredients in crop protection and pesticide formulations.
• Material Science: Potential intermediate in the synthesis of organic electronic materials and specialty polymers due to its fused thienopyridine structure.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations engaged in custom synthesis and process development for client projects.
• Academic Research: Utilized in university and institutional labs for methodological studies in heterocyclic chemistry and reaction mechanism exploration.

Basic Information

Product Name	7-Chlorothieno[3,2-B]Pyridin-5(4H)-One
CAS No.	74695-45-7
Molecular Formula	C7H4ClNOS
Molecular Weight	185.63 g/mol
Synonyms	7-Chloro-4H-thieno[3,2-b]pyridin-5-one; 7-Chloro-5H-thieno[3,2-b]pyridin-5-one; 7-Chlorothieno[3,2-b]pyridin-5(4H)-one; 74695-45-7; Thieno[3,2-b]pyridin-5(4H)-one, 7-chloro-; 7-Chloro-4,5-dihydrothieno[3,2-b]pyridin-5-one
EINECS	Contact for details

Quality Control

Our 7-Chlorothieno[3,2-B]Pyridin-5(4H)-One is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, documenting all critical quality attributes. Our standard is to supply material with a typical purity of ≥97% (HPLC), with higher purity grades available upon request to meet specific research or development needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to prevent moisture absorption. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥97.0%
Related Substances (HPLC)	Total impurities ≤3.0%
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.