Description

2,2,10,10-Tetramethyl-5-[(Trimethylsilyl)Oxy]-3,9-Dioxa-2,10-Disilaundecane is a specialized organosilicon compound, CAS NO 74685-22-6, valued for its role as a versatile protecting group and silylating agent in advanced organic synthesis. Its molecular architecture, featuring multiple silyl ether linkages, provides exceptional stability and selectivity under a range of reaction conditions. This high-purity intermediate is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and material science sectors who require precise control over synthetic pathways.

Application

• Pharmaceutical Intermediate: Used in the multi-step synthesis of complex drug molecules, particularly for protecting hydroxyl groups during sensitive reactions.
• Agrochemical Synthesis: Serves as a key building block in the production of advanced pesticides and herbicides where selective protection is required.
• Material Science Precursor: Employed in the development of silicone-based polymers and hybrid organic-inorganic materials.
• Organic Synthesis Reagent: Acts as a highly effective silylating agent for alcohols and phenols in laboratory and pilot-scale reactions.
• Peptide Chemistry: Utilized for the temporary protection of serine, threonine, or tyrosine side chains in solid-phase peptide synthesis (SPPS).
• Natural Product Isolation & Modification: Aids in the derivatization and purification of sensitive natural compounds.

Basic Information

Item	Detail
Product Name	2,2,10,10-Tetramethyl-5-[(Trimethylsilyl)Oxy]-3,9-Dioxa-2,10-Disilaundecane
CAS No.	74685-22-6
Molecular Formula	C14H34O3Si3
Molecular Weight	350.68 g/mol
Synonyms	1,3-Bis[(tert-butyldimethylsilyl)oxy]-2-[(trimethylsilyl)oxy]propane; 2-[(Trimethylsilyl)oxy]-1,3-bis[(tert-butyldimethylsilyl)oxy]propane; TBDMS-protected glycerol derivative; 1,3-Di-O-tert-butyldimethylsilyl-2-O-trimethylsilyl-sn-glycerol; Silyl ether protecting group reagent; Glycerol 1,3-bis(TBDMS) ether 2-TMS ether; Contact for additional aliases.
EINECS	Contact for details

Quality Control

Every batch of 2,2,10,10-Tetramethyl-5-[(Trimethylsilyl)Oxy]-3,9-Dioxa-2,10-Disilaundecane is manufactured and tested under strict quality management systems to ensure consistency and reliability for critical B2B applications. Our products undergo rigorous quality testing, including chromatographic purity analysis and identity confirmation, to ensure compliance with industry standards. Certificates of Analysis (COA) detailing batch-specific results are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Due to its highly volatile nature, ensure containers are securely sealed when not in use and stored away from strong bases and organic solvents. For long-term storage, consider using an inert atmosphere to maintain product integrity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC/HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.