Description

n-Benzyloxycarbonyl-Indole-3-Carbaldehyde is a versatile and high-purity protected indole derivative, serving as a critical synthetic intermediate in advanced organic synthesis. Its primary value lies in providing a reactive aldehyde functionality on the indole ring while the nitrogen is protected by a benzyloxycarbonyl (Cbz) group, enabling selective and complex molecular transformations. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for the development of novel active ingredients and complex heterocyclic compounds.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of indole-based drug candidates, including kinase inhibitors and serotonin receptor modulators.
• Agrochemical Synthesis: Used in the research and production of novel pesticides and herbicides that utilize the indole scaffold for biological activity.
• Organic Synthesis Reagent: Serves as a pivotal precursor for Pictet-Spengler and other condensation reactions to construct complex polycyclic frameworks.
• Peptidomimetic Research: Employed in the design and synthesis of peptidomimetics and constrained amino acid analogs for medicinal chemistry.
• Material Science: Potential monomer or precursor for functional polymers and advanced organic materials with specific electronic properties.
• Academic & R&D: A standard reagent in university and contract research laboratories for methodological development and exploratory chemistry.

Basic Information

Product Name	n-Benzyloxycarbonyl-Indole-3-Carbaldehyde
CAS No.	74639-50-2
Molecular Formula	C17H13NO3
Molecular Weight	279.29 g/mol
Synonyms	1-[(Benzyloxy)carbonyl]-1H-indole-3-carboxaldehyde; 1H-Indole-3-carboxaldehyde, 1-[(phenylmethoxy)carbonyl]-; 1-Cbz-indole-3-carboxaldehyde; 1-N-Carbobenzoxyindole-3-carboxaldehyde; 1-N-Cbz-indole-3-carboxaldehyde; Indole-3-carboxaldehyde, N-benzyloxycarbonyl-; N-Cbz-3-formylindole; N-Carbobenzyloxyindole-3-carbaldehyde
EINECS	Contact for details

Quality Control

Our n-Benzyloxycarbonyl-Indole-3-Carbaldehyde is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot is subjected to comprehensive analytical testing, including HPLC, NMR, and FTIR, to confirm identity and purity. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We support cGMP compliance for pharmaceutical applications and can tailor specifications to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is easily oxidized (store under inert atmosphere) and is light-sensitive (store away from light). For long-term storage, consider storing under an inert gas such as argon or nitrogen.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.