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n-[(1,2,9,10-Tetramethoxy-6Aα-Aporphin-3-Yl)Methyl]Benzamide Hydrochloride CAS NO 74626-44-1


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CAS No.:74626-44-1

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

n-[(1,2,9,10-Tetramethoxy-6Aα-Aporphin-3-Yl)Methyl]Benzamide Hydrochloride is a high-purity, complex aporphine alkaloid derivative supplied as its hydrochloride salt. This compound is of significant interest for advanced research and development, particularly in the pharmaceutical and life sciences sectors, due to its intricate molecular structure which serves as a key scaffold or intermediate. It is primarily sought by research institutions, pharmaceutical R&D departments, and fine chemical manufacturers engaged in the synthesis of novel bioactive molecules, neuroscience research, and the development of potential therapeutic agents.

Application

  • Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of novel aporphine-based alkaloids for pharmacological evaluation.
  • Neuroscience Research: Used as a reference standard or active compound in studies targeting neurological receptors and pathways.
  • Medicinal Chemistry: Acts as a sophisticated scaffold for structure-activity relationship (SAR) studies and lead optimization programs.
  • Biochemical Research: Employed in enzyme inhibition assays and other in vitro studies to investigate biological activity.
  • Reference Standard: Provides a high-purity benchmark for analytical method development, quality control, and regulatory submissions.
  • Fine Chemical Synthesis: Utilized in multi-step organic synthesis for creating complex, chiral molecules with high added value.

Basic Information

Product Name n-[(1,2,9,10-Tetramethoxy-6Aα-Aporphin-3-Yl)Methyl]Benzamide Hydrochloride
CAS No. 74626-44-1
Molecular Formula C29H30N2O5 • HCl
Molecular Weight 523.02 g/mol (Free base: 486.56 g/mol)
Synonyms N-[(1,2,9,10-Tetramethoxy-6aα-aporphin-3-yl)methyl]benzamide hydrochloride; 3-[(Benzoylamino)methyl]-1,2,9,10-tetramethoxy-6aα-aporphine hydrochloride; Aporphine benzamide derivative hydrochloride; (6aS)-3-[(Benzoylamino)methyl]-1,2,9,10-tetramethoxy-6a,7-dihydro-4H-dibenzo[de,g]quinoline hydrochloride
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Quality Control

Our n-[(1,2,9,10-Tetramethoxy-6Aα-Aporphin-3-Yl)Methyl]Benzamide Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, identity confirmation via spectroscopic methods (IR, NMR, MS), and tests for residual solvents and moisture content. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with your research or production specifications. Our quality commitment supports applications requiring high-purity reference standards and pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, containers must be kept tightly sealed and consideration should be given to storage under an inert atmosphere or with desiccant for long-term preservation. Keep away from incompatible materials.

Specification

Item Specification
Appearance White to off-white powder
Identification (IR) Conforms to structure
Identification (HPLC) Retention time matches reference standard
Purity (HPLC) ≥ 98.0%
Water Content (KF) ≤ 2.0%
Residue on Ignition ≤ 0.5%
Heavy Metals ≤ 20 ppm
Residual Solvents (GC) Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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