Description

Ethyl 5-Chloro-4-Formylthiophene-2-Carboxylate is a high-purity, multi-functional heterocyclic building block essential for advanced organic synthesis. This compound serves as a critical intermediate for constructing complex molecular architectures, particularly in the development of novel active pharmaceutical ingredients (APIs) and functional materials. It is primarily utilized by research and development teams, process chemists, and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries seeking to innovate and scale new products.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of thiophene-based drug candidates, including potential antiviral, anti-inflammatory, and central nervous system (CNS) active compounds.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and insecticides that leverage the thiophene scaffold for enhanced bioactivity.
• Material Science Research: Serves as a building block for organic electronic materials, such as conductive polymers, organic semiconductors, and non-linear optical (NLO) materials.
• Dye and Pigment Manufacturing: Employed in the synthesis of specialized dyes and pigments where the thiophene core contributes to color stability and specific light-absorption properties.
• Custom Synthesis and Contract Manufacturing: An important starting material for custom synthesis projects and contract research organizations (CROs/CMOs) developing proprietary compounds for clients.

Basic Information

Product Name	Ethyl 5-Chloro-4-Formylthiophene-2-Carboxylate
CAS No.	74598-06-4
Molecular Formula	C8H7ClO3S
Molecular Weight	218.66 g/mol
Synonyms	5-Chloro-4-formylthiophene-2-carboxylic acid ethyl ester; Ethyl 5-chloro-4-formyl-2-thiophenecarboxylate; 2-Thiophenecarboxylic acid, 5-chloro-4-formyl-, ethyl ester; 74598-06-4; 5-Chloro-4-formylthiophene-2-carboxylate ethyl ester
EINECS	Contact for details

Quality Control

Our Ethyl 5-Chloro-4-Formylthiophene-2-Carboxylate is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Products undergo rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to confirm identity, potency, and impurity profiles. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from strong oxidizing agents and incompatible materials. The container should be kept tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.