Description

3-Hydroxy-4-Methoxybenzaldehyde-D3 is a deuterated derivative of vanillin, a key aromatic compound, where three hydrogen atoms are replaced with deuterium, serving as a stable isotope-labeled internal standard. This high-purity compound is essential for ensuring the accuracy and reliability of quantitative analytical methods, particularly mass spectrometry. It is primarily required by analytical laboratories, pharmaceutical R&D departments, and manufacturers of high-end flavors and fragrances for precise metabolic studies, quality control, and method validation.

Application

• Internal Standard for Mass Spectrometry (MS): Used as a critical reference compound in quantitative LC-MS and GC-MS analysis for accurate measurement of vanillin and related metabolites in complex matrices.
• Pharmaceutical Research: Employed in pharmacokinetic and metabolic studies to track the absorption, distribution, metabolism, and excretion (ADME) of drug candidates and natural products.
• Flavor and Fragrance Analysis: Facilitates precise quantification of vanillin and its derivatives in food products, beverages, and perfumes for quality assurance and authenticity testing.
• Deuterated Building Block: Acts as a specialized synthon for the synthesis of more complex deuterium-labeled compounds for research and diagnostic applications.
• Environmental and Bioanalytical Testing: Supports trace-level detection and quantification of phenolic aldehydes in environmental samples and biological fluids.

Basic Information

Product Name	3-Hydroxy-4-Methoxybenzaldehyde-D3
CAS No.	74495-73-1
Molecular Formula	C8H5D3O3
Molecular Weight	155.17 g/mol
Synonyms	Deutero Vanillin-d3; Vanillin-d3; 4-Hydroxy-3-methoxybenzaldehyde-d3; 3-Hydroxy-4-methoxybenzaldehyde-2,4,6-d3; (2,4,6-Trideuterio-3-hydroxy-4-methoxybenzaldehyde); 4-Formyl-2-methoxyphenol-d3; Methylprotocatechuic aldehyde-d3; Protocatechuic aldehyde 3-methyl ether-d3
EINECS	Contact for details

Quality Control

Our 3-Hydroxy-4-Methoxybenzaldehyde-D3 is manufactured under strict quality systems to ensure exceptional isotopic purity and chemical integrity, meeting the rigorous demands of analytical and research applications. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing key parameters such as isotopic purity (D-content), chemical purity (by HPLC), and identity confirmation (by NMR and MS). We adhere to relevant industry standards for stable isotope-labeled compounds.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is light-sensitive and should be handled and stored away from direct light exposure to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity (MS)	≥ 98 atom % D
Deuterium Position	2,4,6 (on aromatic ring)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.