Description

2-Methoxy-D3-Phenol is a deuterated derivative of guaiacol, where three hydrogen atoms are replaced by deuterium, a stable isotope of hydrogen. This isotopic labeling is critical for applications requiring precise tracking and analysis, as it provides a distinct molecular signature without altering the chemical's fundamental reactivity. It is primarily utilized by researchers and manufacturers in the pharmaceutical, agrochemical, and analytical chemistry sectors for use as an internal standard, a tracer in metabolic studies, and a building block for labeled compounds.

Application

• Internal Standard for Quantitative Analysis: Used in Gas Chromatography-Mass Spectrometry (GC-MS) and Liquid Chromatography-Mass Spectrometry (LC-MS) for the accurate quantification of guaiacol and related compounds.
• Metabolic Pathway Tracer: Employed in pharmaceutical and biochemical research to study drug metabolism, degradation pathways, and environmental fate using deuterium as a non-radioactive label.
• Deuterated Building Block: Serves as a key synthon in the synthesis of more complex deuterated molecules for research and development.
• NMR Spectroscopy: Acts as a useful standard or reference compound in Nuclear Magnetic Resonance (NMR) spectroscopy due to its distinct isotopic signature.
• Pharmaceutical Impurity Profiling: Aids in the identification and quantification of process-related impurities and degradation products in drug substances and products.
• Agrochemical Research: Used in the development and analysis of labeled pesticides or their metabolites to understand environmental behavior and residue analysis.

Basic Information

Product Name	2-Methoxy-D3-Phenol
CAS No.	74495-69-5
Molecular Formula	C7H5D3O2
Molecular Weight	127.15 g/mol (for C7H5D3O2)
Synonyms	Guaiacol-d3; 2-Methoxyphenol-d3; 1-Hydroxy-2-methoxybenzene-d3; o-Methoxyphenol-d3; Methylcatechol-d3; Deuterated Guaiacol; [2H3]-Guaiacol; (2H3)Guaiacol
EINECS	Contact for details

Quality Control

Our 2-Methoxy-D3-Phenol is produced under controlled conditions to ensure high isotopic and chemical purity, meeting the stringent requirements of research and analytical applications. Each batch is characterized by advanced analytical techniques including NMR, GC-MS, and HPLC to confirm deuterium incorporation and chemical purity. A comprehensive Certificate of Analysis (COA) detailing isotopic purity (D-enrichment), chemical assay, and impurity profile is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity (D-enrichment)	≥ 98 atom % D
Chemical Purity (GC)	≥ 99.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.