Description

Nikkomycin B(Z) CAS NO 74342-20-4 is a potent nucleoside-peptide antibiotic belonging to the nikkomycin family, which acts as a competitive inhibitor of chitin synthase. This compound is of significant interest in agricultural and pharmaceutical research due to its specific antifungal and insecticidal properties. It is primarily utilized by researchers and manufacturers in the agrochemical and life science sectors for developing novel crop protection agents and investigating fungal cell wall biosynthesis.

Application

• Agricultural Fungicide Research: Serves as a key reference standard and active ingredient candidate in the development of new antifungal agents for plant pathogens.
• Insect Growth Regulation: Investigated for its potential use in insect pest management by disrupting chitin synthesis during molting.
• Biochemical Studies: Used as a specific tool compound in enzymatic assays to study the mechanism and inhibition of chitin synthase.
• Pharmaceutical Antifungal Development: Explored in preclinical research for novel therapeutic approaches against chitin-containing human fungal pathogens.
• Microbiology & Cell Biology: Employed in laboratory studies to understand fungal cell wall structure, integrity, and biosynthesis pathways.

Basic Information

Product Name	Nikkomycin B(Z)
CAS No.	74342-20-4
Molecular Formula	C20H25N5O10
Molecular Weight	495.44 g/mol
Synonyms	Nikkomycin B(Z); Nikkomycin B (Z-isomer); Antibiotic PF 1018; Uridine, 5'-O-[(5-amino-1,5-dideoxy-β-D-allofuranuronosyl)amino]carbonyl]-L-phenylalanyl-; L-Phenylalanine, N-[N-[5-O-[(5-amino-1,5-dideoxy-β-D-allofuranuronosyl)amino]carbonyl]-β-D-ribofuranosyl]carbonyl]-; Nikkomycin Z Complex Component
EINECS	Contact for details

Quality Control

Our Nikkomycin B(Z) is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, MS). We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with research-grade specifications.

Storage

Preserve in a tightly closed container, protected from light. Store at 2-8°C in a dry environment. This product is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Heavy Metals	≤ 20 ppm
Residue on Ignition	≤ 0.5%
Microbial Limits	Meets standard for non-sterile substances

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.