Description

Polyoxin A is a nucleoside antibiotic complex produced by *Streptomyces cacaoi* var. *asoensis*, known for its potent and specific fungicidal activity. Its primary value lies in its unique mode of action, inhibiting chitin synthesis in fungal cell walls, making it a critical tool for managing resistant pathogens. This product is essential for agricultural research, the development of eco-friendly crop protection agents, and as a reference standard in analytical and microbiological laboratories.

Application

• Agricultural Fungicide Development: Serves as a key active ingredient or lead compound in formulating bio-fungicides for controlling a wide range of plant diseases, particularly those caused by Ascomycetes and Deuteromycetes.
• Plant Pathology Research: Used as a biochemical tool to study chitin biosynthesis pathways and the mechanisms of fungal growth inhibition.
• Resistance Management: Integrated into pest management programs as a rotation agent with different modes of action to prevent and manage fungicide resistance.
• Reference Standard: Employed in analytical laboratories for the qualitative and quantitative analysis (HPLC, LC-MS) of fungicide formulations and residue studies.
• Microbiological Studies: Used in *in vitro* assays to determine the susceptibility of fungal isolates and to screen for novel antifungal compounds.

Basic Information

Product Name	Polyoxin A
CAS No.	19396-03-3
Molecular Formula	C23H32N6O14
Molecular Weight	616.54 g/mol
Synonyms	Polyoxin A; Polyoxorim; Polyoxin A complex; Antibiotic NK-1006; 1-[(5-O-Carbamoyl-2-deoxy-β-L-lyxofuranosyl)-5-hydroxy-methyl-1,2,3,4-tetrahydro-2,4-dioxopyrimidine]; 5-[[5-Amino-5-deoxy-1-(1,2,3,4-tetrahydro-2,4-dioxo-5-pyrimidinyl)-β-L-ribofuranosyl]amino]-1,5-dideoxy-1-[3,4-dihydro-5-(hydroxymethyl)-2,4-dioxo-1(2H)-pyrimidinyl]-β-L-ribofuranuronic acid; Polyoxin AL
EINECS	243-025-8

Quality Control

Our Polyoxin A is produced and tested under strict quality management protocols to ensure batch-to-batch consistency and reliability for research and development purposes. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, potency, and identification data. While produced to high standards, this material is typically offered as a research-grade chemical and is not currently certified to USP/EP pharmacopeial monographs unless specified.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.