Description

Polyoxin B is a nucleoside antibiotic complex produced by *Streptomyces cacaoi* var. *asoensis*, widely recognized for its potent and specific fungicidal activity. Its primary value lies in its unique mode of action, inhibiting chitin synthase, which makes it highly effective against a broad spectrum of fungal pathogens while being safe for plants, beneficial insects, and mammals. This product is essential for agricultural research, the development of eco-friendly crop protection agents, and as a critical reference standard in analytical and microbiological laboratories.

Application

• Agricultural Fungicide Research & Development: Serves as a key active ingredient or reference compound in formulating novel, targeted fungicides for crop protection.
• Plant Pathology Studies: Used in laboratory research to study fungal growth inhibition, mode of action, and resistance mechanisms.
• Biochemical Research: Employed as a specific inhibitor of chitin synthase in studies of fungal cell wall biosynthesis and related enzymatic pathways.
• Pharmaceutical Intermediates: Acts as a starting material or intermediate for the synthesis of more complex antimicrobial agents.
• Quality Control & Analytical Standards: Provides a high-purity reference standard for HPLC, LC-MS, or microbiological assay methods to ensure product quality and efficacy.
• Integrated Pest Management (IPM): Incorporated into sustainable agriculture programs due to its selective toxicity and favorable environmental profile.

Basic Information

Product Name	Polyoxin B
CAS No.	19396-06-6
Molecular Formula	C17H25N5O13
Molecular Weight	507.41 g/mol
Synonyms	Polyoxin B; Antibiotic NK 101; Polyoxin B Antibiotic; Polyoxin B (antibiotic); Polyoxin B complex; Polyoxin B from *Streptomyces cacaoi*; Polyoxin B, Polyoxorim; Polyoxin-B; Polyoxin B (Polyoxorim); 1-[(5-Amino-5-deoxy-L-allofuranosyl)oxy]-1H-1,2,4-triazole-3-carboxamide, 5-O-carbamoyl derivative
EINECS	243-032-7

Quality Control

Every batch of Polyoxin B is subjected to rigorous analytical testing to ensure identity, purity, and potency meet stringent specifications. Our quality assurance protocols are designed to support research and industrial applications where consistency is critical. A comprehensive Certificate of Analysis (COA), detailing results for assay, purity, and related substances, is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept in a desiccated environment to maintain stability and potency. For long-term storage, consider storing under inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 1.0%
Specific Rotation	Contact for details
Biological Activity	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.