Description

5-Hydroxymethylblasticidin S is a chemically modified derivative of the potent nucleoside antibiotic blasticidin S. This compound matters as a key intermediate and research tool in the development of novel antibiotics and agrochemicals, offering a reactive hydroxymethyl group for further chemical synthesis. It is primarily needed by research institutions and pharmaceutical companies engaged in antibiotic discovery, as well as by agrochemical developers exploring new fungicidal agents for crop protection.

Application

• Antibiotic Research & Development: Serves as a crucial intermediate in the synthesis of novel blasticidin S analogs for evaluating antimicrobial activity.
• Agrochemical Innovation: Used in the research and development of next-generation fungicides for plant disease control.
• Biochemical Studies: Employed as a molecular probe to study protein synthesis inhibition mechanisms in prokaryotic and eukaryotic systems.
• Cell Line Selection: Utilized in genetic engineering and molecular biology for the development of selectable marker systems.
• Pharmaceutical Intermediates: Acts as a building block for the production of more complex therapeutic agents targeting infectious diseases.

Basic Information

Product Name	5-Hydroxymethylblasticidin S
CAS No.	123067-52-7
Molecular Formula	C18H27N7O7
Molecular Weight	453.45 g/mol
Synonyms	5-(Hydroxymethyl)blasticidin S; Blasticidin S, 5-(hydroxymethyl)-; 5-HM-Blastcidin S; 5-Hydroxymethylblasticidin; HM-BlastS; 1-((4-Amino-2-oxo-1(2H)-pyrimidinyl)carbonyl)-5-(hydroxymethyl)-1,2,3,4-tetrahydro-1,4-methano-6,9-epiminobenz[1,2-a]azocin-8(6H)-one
EINECS	Contact for details

Quality Control

Our 5-Hydroxymethylblasticidin S is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity for research applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant industry standards for research-grade biochemicals, ensuring reliable performance in your critical experiments.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below for long-term stability. The product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain integrity. Allow the container to reach room temperature before opening to prevent condensation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.