Description

8-Mercaptooctanoic Acid is a versatile medium-chain thiol fatty acid derivative, serving as a critical building block in advanced organic synthesis. Its bifunctional nature, featuring both a reactive thiol (-SH) and a carboxylic acid (-COOH) group, makes it an essential intermediate for creating custom molecular architectures. This compound is particularly valuable for researchers and manufacturers in the pharmaceutical, polymer, and nanotechnology sectors who require precise surface modification and controlled molecular assembly.

Application

• Pharmaceutical Intermediates: Key precursor in the synthesis of novel drug candidates, particularly for creating disulfide linkages or thioether bonds in active pharmaceutical ingredients (APIs).
• Polymer & Material Science: Used as a chain transfer agent (CTA) in controlled radical polymerization (e.g., RAFT) and as a functional monomer for producing specialty polymers with tailored properties.
• Surface Modification & Self-Assembled Monolayers (SAMs): The thiol group enables strong binding to gold, silver, and other metal surfaces, making it ideal for creating functionalized coatings for sensors, electrodes, and nanotechnology applications.
• Bioconjugation & Linker Chemistry: Employed to create cleavable or stable crosslinks between biomolecules (proteins, peptides) and other entities in diagnostic assays and biotherapeutic development.
• Ligand Synthesis for Catalysis: Serves as a building block for synthesizing specialized ligands used in homogeneous catalysis and metal complexation.
• Cosmetic & Personal Care Ingredients: Intermediate in the production of specialty surfactants and conditioning agents that provide unique benefits to hair and skin formulations.

Basic Information

Product Name	8-Mercaptooctanoic Acid
CAS No.	74328-61-3
Molecular Formula	C8H16O2S
Molecular Weight	176.28 g/mol
Synonyms	8-Sulfanyloctanoic acid; 8-Thiooctanoic acid; Octanoic acid, 8-mercapto-; 8-Mercaptocaprylic acid; 8-Mercapto-n-octanoic acid; 8-SH-Octanoic acid; 8-MOA
EINECS	Contact for details

Quality Control

Our 8-Mercaptooctanoic Acid is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and industrial synthesis. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at 2-8°C to minimize oxidation and degradation. The container should be kept in a cool, dry, and well-ventilated area, separate from strong oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.