Description

[[Estra-1,3,5(10),6-Tetrene-3,11β,17β-Triyl]Tris(Oxy)]Tris(Trimethylsilane) CAS NO 74298-80-9 is a high-purity, organosilicon-protected steroid derivative, serving as a critical advanced intermediate in complex organic synthesis. Its value lies in providing a stable, protected scaffold for the precise construction of novel steroid-based molecules, enabling research and development in highly specialized fields. This compound is essential for pharmaceutical researchers, process chemists, and fine chemical manufacturers focused on developing new therapeutic agents and bioactive compounds.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel steroid-based drug candidates, including potential hormone therapies and enzyme inhibitors.
• Research & Development: Used in academic and industrial R&D labs for exploring new chemical entities (NCEs) and studying structure-activity relationships (SAR) in medicinal chemistry.
• Process Chemistry: Serves as a protected intermediate in multi-step synthetic routes, allowing for selective reactions at other sites on the steroid core.
• Fine Chemical Synthesis: Employed in the production of high-value, low-volume specialty chemicals for advanced material science and biochemical applications.
• Reference Standard: Can be utilized as a chromatographic or spectroscopic reference standard for quality control and analytical method development.

Basic Information

Product Name	[[Estra-1,3,5(10),6-Tetrene-3,11β,17β-Triyl]Tris(Oxy)]Tris(Trimethylsilane)
CAS No.	74298-80-9
Molecular Formula	C30H48O3Si3
Molecular Weight	529.0 g/mol (approx.)
Synonyms	3,11β,17β-Tris(trimethylsilyloxy)estra-1,3,5(10),6-tetraene; Estra-1,3,5(10),6-tetraene-3,11β,17β-triol, tris(trimethylsilyl) ether; Tris-O-trimethylsilyl protected estra-1,3,5(10),6-tetraenetriol; TMS-protected Estra-1,3,5(10),6-tetraenetriol; Steroid TMS Ether Intermediate; 74298-80-9; Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Our [[Estra-1,3,5(10),6-Tetrene-3,11β,17β-Triyl]Tris(Oxy)]Tris(Trimethylsilane) is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing batch-specific results are provided and can be tailored to meet specific client requirements or internal specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.