Description

Bis(3,5-Dimethylphenyl)Chlorophosphine is a specialized organophosphorus compound featuring a reactive P-Cl bond flanked by sterically hindered 3,5-dimethylphenyl groups. This unique structure makes it a valuable ligand precursor and key building block in advanced chemical synthesis, particularly for creating complex phosphine ligands used in catalysis. It is primarily utilized by pharmaceutical researchers, agrochemical developers, and manufacturers of specialty catalysts who require high-purity, structurally defined intermediates for their processes.

Application

• Catalyst Ligand Synthesis: A crucial precursor for synthesizing bulky, electron-rich phosphine ligands used in cross-coupling reactions (e.g., Suzuki, Heck) and hydrogenation catalysis.
• Pharmaceutical Intermediates: Serves as a key building block in the development of active pharmaceutical ingredients (APIs) that incorporate phosphorus-based functional groups.
• Agrochemical Research: Used in the research and development of novel herbicides, insecticides, and fungicides where organophosphorus chemistry is applied.
• Material Science: Employed in the synthesis of phosphorus-containing polymers, flame retardants, and other advanced materials.
• Coordination Chemistry: Acts as a starting material for preparing metal-phosphine complexes with specific steric and electronic properties.
• Organic Synthesis: Utilized in various P-C bond formation reactions to create complex organic molecules for research and development.

Basic Information

Item	Details
Product Name	Bis(3,5-Dimethylphenyl)Chlorophosphine
CAS No.	74289-57-9
Molecular Formula	C16H18ClP
Molecular Weight	276.74 g/mol
Synonyms	Chlorobis(3,5-dimethylphenyl)phosphine; Bis(3,5-xylyl)chlorophosphine; (3,5-Dimethylphenyl)chlorophosphine (dimer form); Chloro-di(3,5-dimethylphenyl)phosphine; Phosphinous chloride, bis(3,5-dimethylphenyl)-; 3,5-Xylylphosphonous dichloride (related); Di(3,5-dimethylphenyl)chlorophosphine
EINECS	Contact for details

Quality Control

Every batch of Bis(3,5-Dimethylphenyl)Chlorophosphine is produced and tested under stringent quality management protocols to ensure high purity and batch-to-batch consistency. Our products undergo rigorous analytical testing, including NMR, HPLC, and titration methods, to meet exacting customer specifications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its moisture-sensitive (hygroscopic) nature, the container should be kept sealed under an inert atmosphere (e.g., nitrogen or argon) when not in use to prevent degradation. Recommended storage temperature is 2-8°C for long-term stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Purity (NMR)	≥ 95.0%
Melting Point	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.