Description

4-(2-Methoxyphenyl)-5-Pyridin-4-Yl-4H-1,2,4-Triazole-3-Thiol is a high-purity, heterocyclic organic compound featuring a 1,2,4-triazole core substituted with methoxyphenyl, pyridinyl, and thiol functional groups. This molecular architecture makes it a valuable and versatile chemical intermediate and research building block for advanced synthesis. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, due to its triazole and pyridine pharmacophores.
• Agrochemical Research: Used as a building block for developing new fungicides, herbicides, and plant growth regulators with potential enhanced efficacy and selectivity.
• Ligand Synthesis in Coordination Chemistry: The thiol and nitrogen donor atoms make it suitable for creating chelating ligands for metal complexes used in catalysis or material science.
• Material Science Precursor: Investigated for the development of advanced organic materials, such as corrosion inhibitors or components for electronic devices.
• Biochemical Research Tool: Employed in academic and industrial research to study enzyme inhibition or as a molecular probe due to its specific heterocyclic structure.
• Custom Synthesis & Contract Manufacturing: A critical starting material for fine chemical manufacturers offering bespoke synthesis services for client-specific molecules.

Basic Information

Item	Details
Product Name	4-(2-Methoxyphenyl)-5-Pyridin-4-Yl-4H-1,2,4-Triazole-3-Thiol
CAS No.	74270-77-2
Molecular Formula	C14H12N4OS
Molecular Weight	284.34 g/mol
Synonyms	4-(2-Methoxyphenyl)-5-(4-pyridinyl)-4H-1,2,4-triazole-3-thiol; 5-(4-Pyridyl)-4-(o-methoxyphenyl)-4H-1,2,4-triazole-3-thiol; 4-(2-Methoxyphenyl)-5-(pyridin-4-yl)-4H-1,2,4-triazole-3-thiol; 74270-77-2; 4H-1,2,4-Triazole-3-thiol, 4-(2-methoxyphenyl)-5-(4-pyridinyl)-; 4-(2-Methoxyphenyl)-5-(4-pyridinyl)-1,2,4-triazole-3-thiol
EINECS	Contact for details

Quality Control

Every batch of our 4-(2-Methoxyphenyl)-5-Pyridin-4-Yl-4H-1,2,4-Triazole-3-Thiol is manufactured under a strict quality management system. We provide comprehensive analytical documentation to ensure traceability and consistency for your critical R&D and production processes. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are supplied with each shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This compound is easily oxidized (store under inert atmosphere) and is light-sensitive (store away from light). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert gas such as nitrogen or argon.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.