Description

5-Chloro-3-Phenethylthiophene-2-Carboxylic Acid is a high-purity, synthetically valuable heterocyclic building block. This compound is a critical intermediate in the research and development of novel active pharmaceutical ingredients (APIs) and advanced organic materials. It is primarily sought after by pharmaceutical R&D laboratories, agrochemical manufacturers, and specialty chemical synthesis companies for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, particularly in medicinal chemistry programs targeting central nervous system (CNS) disorders, inflammation, and metabolic diseases.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, leveraging its unique thiophene core for bioactivity.
• Material Science Research: Serves as a monomer or functional unit in the development of advanced polymers, organic semiconductors, and liquid crystals.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying enzyme function and biological pathways.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) producing bespoke compounds for client projects.

Basic Information

Product Name	5-Chloro-3-Phenethylthiophene-2-Carboxylic Acid
CAS No.	74168-80-2
Molecular Formula	C13H11ClO2S
Molecular Weight	266.74 g/mol
Synonyms	5-Chloro-3-(2-phenylethyl)thiophene-2-carboxylic acid; 2-Thiophenecarboxylic acid, 5-chloro-3-(2-phenylethyl)-; 3-(2-Phenylethyl)-5-chlorothiophene-2-carboxylic Acid; 5-Chloro-3-phenethyl-2-thiophenecarboxylic Acid; 74168-80-2
EINECS	Contact for details

Quality Control

Our 5-Chloro-3-Phenethylthiophene-2-Carboxylic Acid is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. We provide a detailed Certificate of Analysis (COA) with each shipment, ensuring traceability and compliance with your internal specifications and cGMP guidelines where applicable.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents and bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.