Description

H-D-Trp-Oet.Hcl CAS NO 74126-25-3 is a high-purity, protected amino acid derivative specifically engineered for advanced peptide synthesis and pharmaceutical research. This compound serves as a critical chiral building block, enabling the precise construction of complex peptides with defined stereochemistry. It is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and fine chemical sectors who require reliable, high-quality intermediates for developing therapeutic peptides and novel active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A key chiral synthon in the solid-phase and solution-phase synthesis of therapeutic peptides and peptidomimetics.
• Research & Development: Used in academic and industrial R&D for studying peptide structure-activity relationships (SAR) and developing new bioactive compounds.
• API Manufacturing: Serves as a critical raw material in the production of Active Pharmaceutical Ingredients (APIs) that incorporate the D-tryptophan moiety.
• Bioconjugation: Employed in the synthesis of peptide-based conjugates for targeted drug delivery and diagnostic applications.
• Fine Chemical Synthesis: Utilized as a specialized building block in the synthesis of complex organic molecules and custom peptides for various industrial applications.

Basic Information

Item	Detail
Product Name	H-D-Trp-Oet.Hcl
CAS No.	74126-25-3
Molecular Formula	C13H17ClN2O2
Molecular Weight	268.74 g/mol
Synonyms	D-Tryptophan ethyl ester hydrochloride; Ethyl D-tryptophanate hydrochloride; (R)-Ethyl 2-amino-3-(1H-indol-3-yl)propanoate hydrochloride; H-D-Trp-OEt·HCl; D-Trp-OEt·HCl; Ethyl (R)-2-amino-3-(3-indolyl)propionate hydrochloride; D-Tryptophan ethyl ester HCl; D-Tryptophan, ethyl ester, hydrochloride
EINECS	Contact for details

Quality Control

Our H-D-Trp-Oet.Hcl is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC for assay and chiral purity, identification by IR and NMR, and tests for specific impurities. A Certificate of Analysis (COA) detailing all specifications and results is provided with every shipment to guarantee compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.5%
Chiral Purity (HPLC)	≥99.0% (D-isomer)
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.