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Morphinan-3-Ol, 6,14-Endoetheno-4,5-α-Epoxy-7-(2-Hydroxy-5-Methyl- 2-Hexyl)-6-Methoxy-17-Methyl-, Hydrochloride CAS NO 74111-36-7


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CAS No.:74111-36-7

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

Morphinan-3-Ol, 6,14-Endoetheno-4,5-α-Epoxy-7-(2-Hydroxy-5-Methyl-2-Hexyl)-6-Methoxy-17-Methyl-, Hydrochloride is a high-purity synthetic opioid derivative of significant interest in advanced pharmaceutical research and development. This compound matters as a critical intermediate or reference standard for the synthesis and analytical study of potent analgesic agents. It is primarily needed by pharmaceutical R&D laboratories, analytical testing facilities, and academic institutions engaged in neuropharmacology and pain management research.

Application

  • Pharmaceutical Intermediate: Serves as a key building block in the multi-step synthesis of specialized opioid analgesics for research purposes.
  • Reference Standard: Used in analytical chemistry for method development, validation, and quality control testing of related pharmaceutical compounds via HPLC, GC-MS, or LC-MS.
  • Biochemical Research: Employed in in vitro studies to investigate opioid receptor (μ, κ, δ) binding affinity, selectivity, and functional activity.
  • Metabolite Studies: Utilized as an analytical standard for the identification and quantification of drug metabolites in pharmacokinetic and toxicological research.
  • Process Chemistry: Acts as a precursor in the development and scale-up of novel synthetic routes within controlled R&D environments.

Basic Information

Product Name Morphinan-3-Ol, 6,14-Endoetheno-4,5-α-Epoxy-7-(2-Hydroxy-5-Methyl-2-Hexyl)-6-Methoxy-17-Methyl-, Hydrochloride
CAS No. 74111-36-7
Molecular Formula C25H35NO4 • HCl
Molecular Weight 449.99 g/mol (Free base: 413.55 g/mol)
Synonyms 7-(2-Hydroxy-5-methyl-2-hexyl)-6-methoxythevinol hydrochloride; 6,14-endo-Etheno-4,5α-epoxy-7α-(2-hydroxy-5-methyl-2-hexyl)-6-methoxy-17-methylmorphinan-3-ol hydrochloride; Thevinol derivative hydrochloride; 6-Methoxythevinol hydrochloride analog; 7α-[(2-Hydroxy-5-methylhexan-2-yl)]-6,14-endoethenotetrahydrothebaine hydrochloride; 17-Methyl-6,14-endo-etheno-4,5α-epoxy-7α-(2-hydroxy-5-methyl-2-hexyl)-6-methoxymorphinan-3-ol hydrochloride
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Quality Control

Our Morphinan-3-Ol, 6,14-Endoetheno-4,5-α-Epoxy-7-(2-Hydroxy-5-Methyl-2-Hexyl)-6-Methoxy-17-Methyl-, Hydrochloride is produced under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency, meeting the exacting standards required for pharmaceutical research. Certificates of Analysis (COA) detailing comprehensive test results, including assay by HPLC and related substance profiles, are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item Specification
Appearance White to off-white crystalline powder
Identification (IR) Conforms to reference spectrum
Identification (HPLC) Retention time corresponds to reference standard
Assay (HPLC) ≥ 98.0%
Related Substances (HPLC) Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Water Content (KF) ≤ 1.0%
Residue on Ignition ≤ 0.1%
Heavy Metals ≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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