Description

Chloroacetyl Chloride, [1-14C] is a carbon-14 radiolabeled derivative of chloroacetyl chloride, a highly reactive acylating agent. This isotopically labeled compound is essential for conducting detailed metabolic, pharmacokinetic, and environmental fate studies, providing researchers with a powerful tool for precise molecular tracking. It is primarily utilized by scientists and manufacturers in the pharmaceutical, agrochemical, and life science research sectors for developing and analyzing novel compounds.

Application

• Tracer Studies in Pharmaceutical R&D: Used to investigate the absorption, distribution, metabolism, and excretion (ADME) of new drug candidates containing the chloroacetyl moiety.
• Agrochemical Research: Employed in metabolic pathway studies of herbicides, pesticides, and fungicides to understand environmental impact and degradation.
• Biochemical Synthesis: Serves as a radiolabeled building block for synthesizing peptides, modified amino acids, and other bioactive molecules for research purposes.
• Mechanistic Studies: Facilitates the elucidation of reaction mechanisms and biochemical pathways in academic and industrial research settings.
• Regulatory Compliance Testing: Supports studies required for regulatory submissions to agencies like the FDA and EPA by providing definitive data on compound fate.

Basic Information

Product Name	Chloroacetyl Chloride, [1-14C]
CAS No.	74094-67-0
Molecular Formula	C14Cl2CH2O *or* ClCH2C(14Cl)=O
Molecular Weight	~112.93 g/mol (specific activity dependent)
Synonyms	Carbon-14 Labeled Chloroacetyl Chloride; [1-14C]Chloroacetyl Chloride; 2-Chloroacetyl-1-14C Chloride; Monochloroacetyl-1-14C Chloride; Chloroacetic-1-14C Acid Chloride; (Chloroacetyl-1-14C) Chloride; NSC 8435 (labeled)
EINECS	Contact for details

Quality Control

Every batch of our Chloroacetyl Chloride, [1-14C] is produced and analyzed under strict quality protocols to ensure high chemical and radiochemical purity. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) detailing specific activity, radiochemical purity, chemical purity, and solvent composition are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a dedicated, well-ventilated area for radioactive materials at recommended temperatures (typically 2-8°C or as specified on the label). Due to its nature as a strong acid/organic solvent and high volatility, ensure containers are securely sealed and stored upright away from heat and moisture.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR/NMR)	Conforms to structure
Chemical Purity (HPLC/GC)	≥ 98%
Radiochemical Purity (HPLC)	≥ 97%
Specific Activity	Customer specified (mCi/mmol)
Solvent	Typically supplied in benzene, toluene, or as specified

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.