Description

1,4-Dimethoxybenzene-D10 is a deuterated analog of 1,4-dimethoxybenzene, where ten hydrogen atoms are replaced with deuterium, a stable isotope of hydrogen. This high isotopic purity makes it an essential internal standard and reference material for quantitative analysis using mass spectrometry and nuclear magnetic resonance (NMR) spectroscopy. It is primarily utilized by research and development laboratories in the pharmaceutical, agrochemical, and analytical chemistry sectors to ensure accurate measurement and traceability in method development and regulatory compliance.

Application

• Internal Standard for Mass Spectrometry (MS): Used as a deuterated internal standard in LC-MS and GC-MS for the precise quantification of 1,4-dimethoxybenzene and related compounds, correcting for instrument variability and sample preparation losses.
• NMR Spectroscopy Solvent & Reference: Serves as a chemical shift reference or a deuterated solvent component in NMR studies, providing a non-interfering signal for structural elucidation and reaction monitoring.
• Analytical Method Development and Validation: Critical for developing and validating sensitive and specific analytical methods required for regulatory filings with agencies like the FDA and EMA.
• Quality Control and Reference Standard: Acts as a certified reference material (CRM) for calibrating equipment and verifying the accuracy of analytical results in quality control laboratories.
• Organic Synthesis Research: Used as a labeled starting material or intermediate in synthetic chemistry for preparing deuterated target molecules for various research applications.

Basic Information

Product Name	1,4-Dimethoxybenzene-D10
CAS No.	74079-00-8
Molecular Formula	C8D10O2
Molecular Weight	142.23 g/mol
Synonyms	Deuterated Hydroquinone Dimethyl Ether; p-Dimethoxybenzene-D10; 1,4-Bis(methoxy-d3)benzene-2,3,5,6-d4; D10-p-Dimethoxybenzene; Hydroquinone-d10 Dimethyl Ether; [2H10]-1,4-Dimethoxybenzene; Benzene-1,4-diyldimethanol-d10; p-Dimethoxybenzene (deuterated)
EINECS	Contact for details

Quality Control

Every batch of 1,4-Dimethoxybenzene-D10 is manufactured and analyzed under strict quality management systems. We provide comprehensive Certificates of Analysis (COA) detailing key parameters such as isotopic purity (Atom % D), chemical purity (by GC or HPLC), and identity confirmation (by NMR and MS). Our quality commitment ensures the material meets the stringent requirements for use as a reference standard in regulated and research environments.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a cool, dry, and well-ventilated area. Keep the container sealed to prevent moisture absorption and contamination.

Specification

Item	Specification
Appearance	White to off-white crystalline solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC/GC)	≥ 98.0%
Isotopic Purity (Atom % D)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.