Description

8-(3-Phenyl-2-Propenyl)Theophyline is a specialized xanthine derivative, structurally related to theophylline, featuring a cinnamyl (3-phenyl-2-propenyl) side chain. This modification imparts distinct physicochemical and biological properties, making it a valuable intermediate for advanced pharmaceutical research and development. It is primarily utilized by research institutions and pharmaceutical companies engaged in the synthesis of novel therapeutic agents, particularly in the fields of respiratory and neurological research.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel adenosine receptor antagonists and phosphodiesterase (PDE) inhibitors for potential therapeutic applications.
• Biochemical Research: Used as a reference standard or active compound in studies investigating purinergic signaling pathways and their modulation.
• Medicinal Chemistry: Serves as a core scaffold for structure-activity relationship (SAR) studies aimed at developing new drugs for asthma, COPD, and inflammatory conditions.
• Academic Research: Employed in university and institutional labs for pharmacological profiling and mechanistic studies related to xanthine derivatives.
• Pre-clinical Development: Utilized in the early-stage development of new chemical entities (NCEs) targeting G-protein-coupled receptors (GPCRs).

Basic Information

Product Name	8-(3-Phenyl-2-Propenyl)Theophyline
CAS No.	74039-67-1
Molecular Formula	C₁₇H₁₈N₄O₂
Molecular Weight	310.35 g/mol
Synonyms	8-Cinnamyltheophylline; 8-(Cinnam-3-yl)theophylline; Theophylline, 8-(3-phenyl-2-propenyl)-; 1H-Purine-2,6-dione, 3,7-dihydro-1,3-dimethyl-8-(3-phenyl-2-propen-1-yl)-; 1,3-Dimethyl-8-(3-phenylprop-2-en-1-yl)-3,7-dihydro-1H-purine-2,6-dione
EINECS	Contact for details

Quality Control

Our 8-(3-Phenyl-2-Propenyl)Theophyline is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, identity confirmation by IR and NMR spectroscopy, and residual solvent analysis to ensure it meets high-grade standards suitable for research applications. A detailed Certificate of Analysis (COA) is provided with every shipment to guarantee traceability and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials and sources of ignition.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.