Description

Theophylline, 8-Butyl-, Hydrochloride is a chemically modified derivative of theophylline, designed for enhanced pharmacological research and development. This compound matters for its potential to offer improved solubility and bioavailability profiles compared to its parent molecule, making it a valuable intermediate for creating novel therapeutic agents. It is primarily needed by pharmaceutical R&D laboratories, academic research institutions, and fine chemical manufacturers focused on developing next-generation respiratory and cardiovascular treatments.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel xanthine-based drugs targeting adenosine receptors.
• Biochemical Research: Used as a reference standard or active compound in studies of bronchodilation, vasodilation, and anti-inflammatory pathways.
• Preclinical Development: Serves as a candidate molecule for pharmacokinetic and pharmacodynamic studies in animal models.
• Academic Research: Employed in university and institutional labs for investigating structure-activity relationships (SAR) within the xanthine chemical class.
• Fine Chemical Synthesis: Intermediate for the custom synthesis of more complex, targeted molecules for specialized therapeutic applications.

Basic Information

Product Name	Theophylline, 8-Butyl-, Hydrochloride
CAS No.	74039-65-9
Molecular Formula	C13H20N4O2 • HCl
Molecular Weight	300.79 g/mol (Free base: 264.33 g/mol)
Synonyms	8-Butyltheophylline Hydrochloride; 1,3-Dimethyl-8-butylxanthine Hydrochloride; 8-n-Butyltheophylline HCl; 8-Butyl-1,3-dimethyl-3,7-dihydro-1H-purine-2,6-dione Hydrochloride; 8-Butyl-1,3-dimethylxanthine Hydrochloride; 8BT HCl; 8-Butyl-Theophylline HCl
EINECS	Contact for details

Quality Control

Our Theophylline, 8-Butyl-, Hydrochloride is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including identification, purity assay, and impurity profiling, to ensure it meets the high standards required for research and development. A Certificate of Analysis (COA) detailing all test results is provided with every shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Loss on Drying	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm
Related Substances (HPLC)	Total impurities ≤2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.