Description

Avoparcin Alpha is a glycopeptide antibiotic belonging to the avoparcin complex, specifically isolated as the alpha component. This compound is valued for its potent antibacterial activity, particularly against Gram-positive organisms. It is primarily utilized in research and development settings within the pharmaceutical and life sciences industries for studying antibiotic mechanisms and resistance.

Application

• Pharmaceutical Research & Development: Used as a reference standard and active ingredient in studies focused on glycopeptide antibiotics, their mode of action, and bacterial resistance mechanisms.
• Microbiological Studies: Employed in in vitro assays to determine the susceptibility of Gram-positive bacterial strains.
• Veterinary Research: Historically studied for growth promotion applications in animal husbandry; current research focuses on understanding the implications of its past use.
• Biochemical Analysis: Serves as a critical reagent in enzymatic and binding studies related to bacterial cell wall synthesis.
• Antibiotic Resistance Monitoring: Used in surveillance programs to track the prevalence and transfer of vancomycin-resistance genes (e.g., vanA) in bacterial populations.

Basic Information

Product Name	Avoparcin Alpha
CAS No.	73957-86-5
Molecular Formula	C89H99Cl2N9O33
Molecular Weight	~1909.2 g/mol
Synonyms	Avoparcin A; Antibiotic X-5108 Alpha; Avoparcin Component A; (3S,6R,7R,22R,36S,38aS)-44-[[2-O-(3-Amino-2,3,6-trideoxy-α-L-lyxo-hexopyranosyl)-β-D-glucopyranosyl]oxy]-6-[[(2S,5S,6S)-5-amino-2-carbamimidamido-6-methyl-4-oxooxan-2-yl]carbamoyl]-22-[(2R)-2-amino-2-phenylacetamido]-7,38a-dihydroxy-3-[(2R)-1-hydroxypropan-2-yl]-2,5,24,27,32,35-hexaoxo-11,13-dithia-1,4,23,26,31,34-hexaazaoctacyclo[27.10.3.1³,⁸.1¹⁰,¹⁵.0²,²⁷.0¹⁴,¹⁹.0²⁰,²⁵.0³⁶,⁴¹]dotetraconta-8,14,16,18,20(41),21,25,37,39,43-decaene-36-carboxylic acid
EINECS	Contact for details

Quality Control

Our Avoparcin Alpha is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing to ensure identity, purity, and potency. A comprehensive Certificate of Analysis (COA) detailing specifications such as assay, related substances, and residual solvents is provided with every shipment to support your research and compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept in a desiccated environment to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 1.0%
Related Substances (HPLC)	Total impurities ≤ 3.0% Any single impurity ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.