Description

Tramadol Hydrochloride is a centrally acting synthetic opioid analgesic used for the management of moderate to moderately severe pain. Its primary value lies in its dual mechanism of action, combining mu-opioid receptor agonism with inhibition of norepinephrine and serotonin reuptake. This product is essential for pharmaceutical manufacturers developing pain management formulations, including tablets, capsules, and injectable solutions.

Application

• Pharmaceutical Active Ingredient (API): Primary use in the formulation of prescription analgesic medications.
• Tablet and Capsule Manufacturing: Direct compression or granulation processes for oral solid dosage forms.
• Injectable Solutions: Production of sterile solutions for intramuscular or intravenous administration in clinical settings.
• Generic Drug Production: Sourcing of the key API for cost-effective generic versions of branded pain relievers.
• Veterinary Medicine: Used in certain veterinary applications for post-operative pain control in animals.
• Clinical Research: Serves as a reference standard or active component in pharmacological and pain management studies.

Basic Information

Product Name	Tramadol Hydrochloride
CAS No.	73806-49-2
Molecular Formula	C16H25NO2 • HCl
Molecular Weight	299.84 g/mol
Synonyms	(1R,2R)-2-[(Dimethylamino)methyl]-1-(3-methoxyphenyl)cyclohexanol hydrochloride; Tramadol HCl; CG 315; E-265; Tramal; Ultram; Zydol; Tradol; Contramal; Ralivia; Rybix ODT; Ryzolt
EINECS	Contact for details

Quality Control

Our Tramadol Hydrochloride is manufactured under strict quality systems. We ensure compliance with major pharmacopoeial standards, including USP and EP monographs. Every batch undergoes comprehensive analytical testing for identity, purity, and impurity profiles. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming specifications for assay, related substances, residual solvents, and microbiological quality.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept in a dry environment to prevent degradation and clumping.

Specification

Item	Specification
Appearance	White or almost white crystalline powder
Identification (IR)	Conforms to standard
Identification (HPLC)	Retention time corresponds to reference
Assay (HPLC)	98.5% - 101.5% (on anhydrous basis)
Water (KF)	≤ 0.5%
Related Substances (HPLC)	Individual impurity: ≤ 0.1% Total impurities: ≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Microbial Limits	Conforms to EP/USP requirements

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.