Description

n-(Tetrahydro-2-Oxothiophen-3-Yl)Phosporamidic Acid Dibenzyl Ester is a specialized organophosphorus compound with a unique heterocyclic structure, serving as a critical building block in advanced organic synthesis. This high-purity intermediate is valued for its role in constructing complex molecules, particularly in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals. It is essential for research and production teams in the pharmaceutical, agrochemical, and fine chemical industries seeking to develop new compounds with targeted biological activity.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly those targeting neurological or metabolic pathways.
• Agrochemical Synthesis: Used in the production of advanced pesticides, herbicides, and plant growth regulators where its phosphoramidate moiety is incorporated for bioactivity.
• Ligand and Catalyst Development: Serves as a precursor for creating novel phosphorus-containing ligands used in asymmetric catalysis and metal complexation.
• Peptidomimetic Research: Its structure is applicable in the design of peptide analogs and enzyme inhibitors in medicinal chemistry.
• Chemical Biology Probes: Utilized in the synthesis of molecular probes for studying biochemical processes and enzyme mechanisms.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects requiring high-fidelity phosphoramidate chemistry.

Basic Information

Item	Details
Product Name	n-(Tetrahydro-2-Oxothiophen-3-Yl)Phosporamidic Acid Dibenzyl Ester
CAS No.	73805-83-1
Molecular Formula	C19H22NO4PS
Molecular Weight	391.42 g/mol
Synonyms	Phosphoramidic acid, N-(tetrahydro-2-oxo-3-thienyl)-, dibenzyl ester; Dibenzyl N-(tetrahydro-2-oxothiophen-3-yl)phosphoramidate; 3-[(Dibenzyloxyphosphoryl)amino]dihydrothiophen-2(3H)-one; Butyrolactam phosphoramidate dibenzyl ester (derivative); NSC 339586
EINECS	Contact for details

Quality Control

Our n-(Tetrahydro-2-Oxothiophen-3-Yl)Phosporamidic Acid Dibenzyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure it meets the high standards required for research and synthesis. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from heat, open flames, and incompatible materials. Due to its light-sensitive nature, handling should be conducted under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.