Description

1,1,1,2,3,3-Hexadeuterio-3-Phenyl-Propan-2-Amine is a deuterated analog of amphetamine, specifically designed for advanced research and analytical applications. This compound is critical for use as an internal standard in mass spectrometry, enabling precise quantification and metabolic studies in complex biological matrices. It is primarily utilized by pharmaceutical R&D laboratories, forensic analysis units, and academic institutions conducting pharmacokinetic and neurochemical research.

Application

• Internal Standard for Mass Spectrometry (MS): Essential for accurate quantification in LC-MS/MS and GC-MS methods due to its isotopic labeling, minimizing matrix effects.
• Metabolite Tracing & Pharmacokinetic Studies: Used in drug metabolism and disposition (DMPK) research to track the fate of amphetamine-related compounds.
• Forensic and Clinical Toxicology: Serves as a reference standard for the definitive identification and measurement of amphetamines in biological samples.
• Neuropharmacology Research: Employed in studies investigating the mechanisms of action, receptor binding, and neurotransmitter release of phenethylamines.
• Deuterium Labeling Studies: Used in mechanistic organic chemistry and spectroscopy to study reaction pathways and molecular structures.
• Quality Control & Method Development: Integral for developing and validating analytical methods in pharmaceutical quality assurance laboratories.

Basic Information

Product Name	1,1,1,2,3,3-Hexadeuterio-3-Phenyl-Propan-2-Amine
CAS No.	73758-26-6
Molecular Formula	C9H7D6N
Molecular Weight	141.24 g/mol
Synonyms	d6-Amphetamine; Deuterated Amphetamine; 1,1,1,2,3,3-Hexadeutero-3-phenylpropan-2-amine; (RS)-1-Phenyl-2-aminopropane-d6; (±)-α-Methylbenzeneethanamine-d6; Amphetamine-d6; Benzeneeethanamine, α-methyl-, d6-; Racemic Amphetamine-d6
EINECS	Contact for details

Quality Control

Our 1,1,1,2,3,3-Hexadeuterio-3-Phenyl-Propan-2-Amine is manufactured under strict quality systems to ensure high chemical and isotopic purity, essential for reliable analytical results. Each batch is supported by a comprehensive Certificate of Analysis (COA) detailing parameters such as isotopic enrichment (D-content), chemical purity, and solvent residues. We adhere to relevant standards for research chemicals, and specifications can be tailored to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its highly volatile nature, ensure containers are securely sealed when not in use to prevent loss and contamination. Keep away from heat and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid / oil
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity (Deuterium Enrichment)	≥ 98 atom % D
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.