Description

1,1-Dideuterio-1-Phenyl-Propan-2-Amine is a deuterated analog of amphetamine, where two hydrogen atoms at the 1-position are replaced with the stable isotope deuterium. This isotopic labeling is crucial for advanced research and development, particularly in the fields of analytical chemistry and pharmacology. It serves as a key intermediate and reference standard for scientists in pharmaceutical R&D, forensic analysis, and metabolic studies, enabling precise tracking and quantification in complex systems.

Application

• Pharmaceutical Research & Development: Used as a stable isotope-labeled internal standard for the accurate quantification of amphetamine and related compounds in bioanalytical methods like LC-MS/MS.
• Metabolic Pathway Studies: Employed in tracer studies to investigate the metabolic fate, pharmacokinetics, and degradation pathways of phenethylamine derivatives.
• Forensic Analysis & Toxicology: Serves as a critical reference material for the definitive identification and confirmation of substances in forensic laboratories, ensuring analytical rigor.
• Deuterated Building Block Synthesis: Acts as a specialized synthon for the preparation of more complex deuterated molecules used in drug discovery and development.
• NMR Spectroscopy: Utilized as a probe in nuclear magnetic resonance (NMR) studies due to the distinct properties of deuterium, aiding in structural elucidation and mechanistic research.
• Quality Control & Method Validation: Essential for developing and validating highly sensitive and specific analytical methods in regulatory and quality control environments.

Basic Information

Item	Detail
Product Name	1,1-Dideuterio-1-Phenyl-Propan-2-Amine
CAS No.	73758-25-5
Molecular Formula	C9H11D2N
Molecular Weight	137.22 g/mol (approx.)
Synonyms	1,1-Dideutero-1-phenyl-2-propanamine; (±)-1,1-Dideuteroamphetamine; d2-Amphetamine (1,1-d2); 1-Phenyl-2-aminopropane-1,1-d2; DL-Amphetamine-1,1-d2; 1,1-Dideuterio-α-methylbenzeneethanamine; Benzenee thanamine, α-methyl-1,1-d2-
EINECS	Contact for details

Quality Control

Our 1,1-Dideuterio-1-Phenyl-Propan-2-Amine is produced and handled under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including NMR for structural and isotopic purity confirmation and HPLC for chemical purity assessment. We provide a detailed Certificate of Analysis (COA) with each shipment, documenting key parameters such as assay, deuterium enrichment, and impurity profile to ensure it meets the exacting standards required for research and analytical applications.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry place at a controlled room temperature (15-25°C). Due to its sensitivity to oxidation, the container should be sealed immediately after use to minimize exposure to air.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid / oil
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Deuterium Enrichment	≥ 98 atom % D
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.