Description

2-(Acetylamino)-2-[(7-Amino-1H-Indol-3-Yl)Methyl]Malonic Acid Diethyl Ester is a specialized, high-purity synthetic intermediate of significant interest in advanced organic synthesis. This compound matters for its unique molecular architecture, which incorporates both indole and malonate ester functionalities, making it a versatile building block for constructing complex heterocyclic systems. It is primarily needed by research institutions and pharmaceutical development companies engaged in the synthesis of novel bioactive molecules, including potential drug candidates and advanced materials. The CAS number for this product is 73747-60-1.

Application

This advanced chemical intermediate serves as a critical precursor in several high-value research and development applications:

• Pharmaceutical Research & Development: As a key building block in the synthesis of novel indole-based drug candidates, particularly for central nervous system (CNS) and oncological targets.
• Organic Synthesis & Medicinal Chemistry: Utilized in complex multi-step syntheses to introduce functionalized indole and amino acid-like structures into target molecules.
• Chemical Biology & Proteomics: Potential use in the development of chemical probes, enzyme inhibitors, or affinity tags due to its reactive amine and ester groups.
• Agrochemical Intermediate: Serves as a precursor in the development of new crop protection agents and plant growth regulators.
• Academic & Contract Research: Employed in university and CRO laboratories for methodological development and the exploration of new chemical spaces.

Basic Information

Product Name	2-(Acetylamino)-2-[(7-Amino-1H-Indol-3-Yl)Methyl]Malonic Acid Diethyl Ester
CAS No.	73747-60-1
Molecular Formula	C19H25N3O5
Molecular Weight	375.42 g/mol
Synonyms	Diethyl 2-acetamido-2-[(7-amino-1H-indol-3-yl)methyl]malonate; 2-(Acetylamino)-2-[(7-Amino-1H-Indol-3-Yl)Methyl]Malonic Acid Diethyl Ester; 2-Acetamido-2-[(7-amino-1H-indol-3-yl)methyl]malonic acid diethyl ester; 73747-60-1; Malonic acid, 2-(acetylamino)-2-[(7-amino-1H-indol-3-yl)methyl]-, diethyl ester; Diethyl (2-acetamido-2-((7-amino-1H-indol-3-yl)methyl)malonate)
EINECS	Contact for details

Quality Control

Our 2-(Acetylamino)-2-[(7-Amino-1H-Indol-3-Yl)Methyl]Malonic Acid Diethyl Ester is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity for research applications. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) are available upon request, detailing key parameters such as purity (HPLC), identity (NMR, IR), and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to prevent moisture absorption. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	Off-white to light yellow powder or crystalline solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95% (Research Grade)
Purity (HPLC)	≥ 98% (Premium Grade)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.