Description

Diethyl Ethyl-D5-Phenylmalonate is a deuterated derivative of diethyl ethylphenylmalonate, a valuable synthetic intermediate in organic chemistry. This compound is specifically designed for applications requiring stable isotope labeling, offering enhanced precision in analytical and research methodologies. It is primarily utilized by researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials sectors for the development of deuterated active ingredients and as a tracer in metabolic and pharmacokinetic studies.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of deuterated drug candidates, enhancing metabolic stability and enabling drug metabolism and pharmacokinetics (DMPK) studies.
• Agrochemical Research: Used in the development of deuterated pesticides and herbicides to study environmental fate and degradation pathways.
• Analytical Standard: Serves as a high-purity internal standard or reference material in mass spectrometry (MS) and nuclear magnetic resonance (NMR) spectroscopy for quantitative analysis.
• Isotope Labeling: Essential for mechanistic studies in organic synthesis and catalysis, where deuterium tracing provides insights into reaction pathways.
• Material Science: Potential precursor for synthesizing deuterated organic semiconductors or liquid crystals for specialized electronic applications.
• Metabolite Synthesis: Used to prepare deuterated metabolites for use as authentic standards in bioanalytical assays.

Basic Information

Item	Detail
Product Name	Diethyl Ethyl-D5-Phenylmalonate
CAS No.	73738-03-1
Molecular Formula	C15H15D5O4
Molecular Weight	269.34 g/mol (approx.)
Synonyms	Diethyl (Ethyl-d5)phenylmalonate; Ethyl-D5-phenylmalonic Acid Diethyl Ester; Diethyl (Pentadeuteroethyl)phenylmalonate; Diethyl Ethyl(phenyl)malonate-d5; Phenylmalonic Acid Diethyl Ester-d5; (Ethyl-d5)phenylmalonic Acid Diethyl Ester; Deuterated Diethyl Ethylphenylmalonate
EINECS	Contact for details

Quality Control

Our Diethyl Ethyl-D5-Phenylmalonate is produced under strict quality management systems to ensure batch-to-batch consistency and high isotopic purity. Each lot is characterized by advanced analytical techniques including NMR, GC-MS, and HPLC to confirm chemical and isotopic identity, assay, and impurity profile. A comprehensive Certificate of Analysis (COA) detailing purity, deuterium enrichment, and solvent residues is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from strong bases and incompatible materials. For long-term storage under inert atmosphere, please contact our technical team for specific recommendations.

Specification

Item	Specification
Appearance	Colorless to pale yellow clear liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Deuterium Enrichment (NMR/MS)	≥ 98 atom % D
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.