Description

5,6-Dichloro-2-Phenyl-1,3,2-Benzodioxaborole is a specialized organoboron compound that serves as a versatile synthetic intermediate in advanced chemical synthesis. Its unique benzodioxaborole scaffold, functionalized with chloro and phenyl substituents, makes it a valuable precursor for constructing complex molecular architectures, particularly in the development of functional materials and active pharmaceutical ingredients. This high-purity chemical is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and materials science sectors who require reliable building blocks for cross-coupling reactions and ligand synthesis.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates, particularly those targeting boron neutron capture therapy (BNCT) or requiring boron-containing pharmacophores.
• Agrochemical Synthesis: Used as a precursor for developing advanced pesticides and herbicides with specific modes of action.
• Material Science: Serves as a monomer or cross-linking agent in the production of specialty polymers, resins, and organic electronic materials.
• Ligand Precursor: Utilized in the preparation of sophisticated ligands for catalysis, including those used in Suzuki-Miyaura and other palladium-catalyzed cross-coupling reactions.
• Chemical Research: A critical reagent in academic and industrial R&D for exploring new organoboron chemistry and developing novel synthetic methodologies.
• Coordination Chemistry: Acts as a chelating agent or a component in the synthesis of metal-organic frameworks (MOFs) and other coordination polymers.

Basic Information

Product Name	5,6-Dichloro-2-Phenyl-1,3,2-Benzodioxaborole
CAS No.	73688-88-7
Molecular Formula	C12H7BCl2O2
Molecular Weight	265.90 g/mol
Synonyms	2-Phenyl-5,6-dichloro-1,3,2-benzodioxaborole; 5,6-Dichloro-2-phenylbenzo[d][1,3,2]dioxaborole; 1,3,2-Benzodioxaborole, 5,6-dichloro-2-phenyl-; Phenyl-5,6-dichlorobenzodioxaborole; 73688-88-7; 5,6-Dichloro-2-phenyl-1,3,2-benzodioxaborol; Dichlorophenylbenzodioxaborole
EINECS	Contact for details

Quality Control

Our 5,6-Dichloro-2-Phenyl-1,3,2-Benzodioxaborole is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity. Each lot is analyzed using advanced techniques including HPLC, GC, and NMR spectroscopy. We provide comprehensive Certificates of Analysis (COA) detailing purity, identity, and impurity profiles upon request, supporting compliance with cGMP and ISO 9001 standards for research and development use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic and easily oxidized nature, it is recommended to store the material under an inert atmosphere (e.g., nitrogen or argon) in a desiccated environment to maintain stability and prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.