Description

Phthalic Acid, [Ring-14C(U)] is a carbon-14 labeled isotopologue of phthalic acid, a key aromatic dicarboxylic acid. This radiolabeled compound is essential for precise metabolic and environmental fate studies, providing critical traceability in research. It is primarily used by scientists and researchers in the pharmaceutical, agrochemical, and environmental sectors for advanced analytical applications such as ADME (Absorption, Distribution, Metabolism, and Excretion) studies and degradation pathway analysis.

Application

• Tracer Studies in Metabolism Research: Used as a radiolabeled tracer to investigate the metabolic pathways and biotransformation of phthalates and related compounds in biological systems.
• Environmental Fate and Degradation Analysis: Employed to study the photodegradation, biodegradation, and environmental persistence of phthalic acid derivatives in soil and water.
• Pharmaceutical ADME Studies: A vital tool for tracking the absorption, distribution, metabolism, and excretion profiles of drug candidates or contaminants that metabolize to phthalic acid.
• Polymer and Plasticizer Research: Serves as a labeled precursor or degradation marker in studies concerning the synthesis, stability, and leaching of phthalate-based plasticizers from polymers.
• Analytical Method Development: Used as an internal standard or reference material in the development and validation of sensitive analytical methods like LC-MS (Liquid Chromatography-Mass Spectrometry) and scintillation counting.
• Biochemical Pathway Elucidation: Applied in enzymology and microbiology to trace specific biochemical reactions and catabolic pathways involving aromatic acids.

Basic Information

Product Name	Phthalic Acid, [Ring-14C(U)]
CAS No.	73607-73-5
Molecular Formula	C8H614C2O4 or C8H6O4 (with 14C label)
Molecular Weight	~168.11 g/mol (specific activity dependent)
Synonyms	1,2-Benzenedicarboxylic Acid, [Ring-14C(U)]; [14C]-Phthalic Acid; Radiolabeled Phthalic Acid; Carbon-14 Labeled Phthalic Acid; Benzene-1,2-dicarboxylic Acid-[ring-14C(U)]; o-Phthalic Acid-[ring-14C(U)]; Isotopically Labeled Phthalic Acid; Tracer Phthalic Acid
EINECS	Contact for details

Quality Control

Every batch of Phthalic Acid, [Ring-14C(U)] is manufactured and analyzed under strict quality control protocols to ensure high chemical and radiochemical purity, specific activity, and radiochemical stability. Comprehensive Certificates of Analysis (COA) are provided, detailing parameters such as radionuclidic purity, radiochemical purity (by HPLC), chemical purity, and specific activity. Our quality system is designed to meet the stringent requirements of research and regulatory submission standards.

Storage

Preserve in a tightly closed container, protected from light. Store at 2-8°C or as specified on the label or COA. Due to its hygroscopic (moisture-sensitive) nature, the product should be stored in a cool, dry place. Handle and store in accordance with all applicable radiation safety regulations and guidelines.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98% (chemical purity)
Radiochemical Purity (HPLC)	≥ 97%
Specific Activity	Customizable (mCi/mmol)
Solvent (if supplied as solution)	Specified on COA

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.