Description

1H-Indole-4,5,6,7-D4 is a deuterium-labeled isotopologue of indole, a fundamental heterocyclic aromatic compound, where four hydrogen atoms at the 4, 5, 6, and 7 positions are replaced with deuterium (CAS NO 73509-22-5). This stable isotope-labeled compound is essential for advanced analytical research, providing a critical internal standard for precise quantification and metabolic pathway tracing. It is primarily utilized by researchers and developers in the pharmaceutical, agrochemical, and life science sectors for applications in mass spectrometry, NMR spectroscopy, and drug metabolism studies.

Application

• Internal Standard for Mass Spectrometry (MS): Used as a quantitative reference standard in LC-MS and GC-MS analyses to ensure accuracy in pharmacokinetic and bioanalytical studies.
• Metabolic Pathway Tracing: Enables the detailed tracking and identification of metabolites in drug discovery and development processes.
• NMR Spectroscopy Studies: Serves as a valuable tool in nuclear magnetic resonance spectroscopy for structural elucidation and dynamic studies of indole-containing compounds.
• Pharmaceutical Research: Critical for the development and validation of analytical methods for indole-based active pharmaceutical ingredients (APIs).
• Biochemical Research: Facilitates investigations into tryptophan metabolism and related biochemical pathways.
• Agrochemical Analysis: Employed in the environmental and residue analysis of indole-derived pesticides and plant growth regulators.

Basic Information

Product Name	1H-Indole-4,5,6,7-D4
CAS No.	73509-22-5
Molecular Formula	C8D4H5N
Molecular Weight	121.18 g/mol
Synonyms	Indole-4,5,6,7-d4; 1H-Indole-d4 (4,5,6,7); 4,5,6,7-Tetradeutero-1H-indole; Benzopyrrole-d4; 2,3-Benzopyrrole-d4; 1-Benzazole-d4; [4,5,6,7-2H4]Indole
EINECS	Contact for details

Quality Control

Our 1H-Indole-4,5,6,7-D4 is manufactured under strict quality protocols to ensure high isotopic purity and chemical integrity, meeting the stringent requirements of research and analytical applications. Each batch is supported by a comprehensive Certificate of Analysis (COA) detailing isotopic enrichment, chemical purity, and analytical results. We adhere to relevant industry standards for stable isotope-labeled compounds to guarantee reliable and reproducible performance in your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry, well-ventilated area. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥98.0%
Isotopic Purity (D-content)	≥98 atom % D
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.