Description

(R)-3-Amino-3-(2-Thienyl)-Propionic Acid is a chiral, non-proteinogenic amino acid derivative featuring a thiophene ring, making it a valuable building block in asymmetric synthesis. Its primary significance lies in its role as a key chiral intermediate for the development of novel pharmaceuticals and bioactive compounds. This high-purity intermediate is essential for research and production in the pharmaceutical industry, particularly for synthesizing active pharmaceutical ingredients (APIs) and complex molecules requiring specific stereochemistry.

Application

• Pharmaceutical Intermediate: A critical chiral building block for the synthesis of novel Active Pharmaceutical Ingredients (APIs), especially in central nervous system (CNS) and metabolic disorder research.
• Asymmetric Synthesis: Used as a starting material or chiral auxiliary in stereoselective organic synthesis to introduce the (R)-configuration into target molecules.
• Peptidomimetics & Drug Discovery: Incorporated into peptide analogs and peptidomimetics to enhance metabolic stability, bioavailability, and receptor binding affinity.
• Ligand & Catalyst Development: Serves as a precursor for creating chiral ligands and organocatalysts used in enantioselective transformations.
• Biochemical Research: Utilized in studies of enzyme inhibition, receptor-ligand interactions, and as a probe in medicinal chemistry.
• Agrochemical Synthesis: Potential intermediate in the development of chiral agrochemicals with improved efficacy and environmental profiles.

Basic Information

Product Name	(R)-3-Amino-3-(2-Thienyl)-Propionic Acid
CAS No.	73495-10-0
Molecular Formula	C7H9NO2S
Molecular Weight	171.22 g/mol
Synonyms	(R)-3-Amino-3-(thiophen-2-yl)propanoic acid; (R)-β-Amino-β-(2-thienyl)propionic acid; (R)-3-Amino-3-(2-thienyl)propanoic acid; D-3-Amino-3-(2-thienyl)propionic acid; (R)-3-Amino-3-(2-thienyl)propionate; (R)-2-Thienyl-β-alanine; (R)-3-Amino-3-(2-thienyl)propanoate; (R)-3-Amino-3-(2-thienyl)-propanoic acid
EINECS	Contact for details

Quality Control

Our (R)-3-Amino-3-(2-Thienyl)-Propionic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity analysis by HPLC, to ensure it meets the high standards required for pharmaceutical R&D and production. Certificates of Analysis (COA) detailing identity, purity, enantiomeric excess, and impurity profiles are provided with every shipment. We support compliance with cGMP, ICH Q7, and other relevant pharmaceutical guidelines for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation due to moisture absorption. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.