Description

S-Nitrosodithiothreitol is a specialized biochemical reagent primarily used as a nitric oxide (NO) donor in research and development. This compound is critical for studying the physiological and pathological roles of nitric oxide signaling in biological systems. It is an essential tool for researchers in pharmaceutical development, biochemistry, and cell biology, enabling controlled NO release in experimental models.

Application

• Biochemical Research: As a controlled nitric oxide (NO) donor for studying cell signaling pathways, vasodilation, and neurotransmission.
• Pharmaceutical R&D: Used in the development and screening of drugs targeting nitric oxide synthase (NOS) and related cardiovascular or neurological conditions.
• Cell Biology Studies: Employed to investigate the effects of NO on apoptosis, inflammation, and immune response in cell culture models.
• Enzymology: Serves as a substrate or modulator in enzymatic studies related to S-nitrosylation and redox biology.
• Neuroscience Research: Applied in studies exploring the role of NO as a neurotransmitter and neuromodulator.
• Reference Standard: Used as a high-purity analytical standard for method development and quality control in analytical laboratories.

Basic Information

Product Name	S-Nitrosodithiothreitol
CAS No.	73427-32-4
Molecular Formula	C4H8N2O3S2
Molecular Weight	196.25 g/mol
Synonyms	S-Nitrosyl-DL-dithiothreitol; S-NO-DTT; Nitrosodithiothreitol; DTT-NO; (2S,3S)-1,4-Dimercapto-2,3-butanediol S-nitrosothiol; S-Nitroso-DTT; S-Nitrosothiol-DTT; Nitric Oxide DTT Donor
EINECS	Contact for details

Quality Control

Our S-Nitrosodithiothreitol is manufactured under strict quality protocols to ensure high purity and batch-to-batch consistency, suitable for sensitive research applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant quality management standards to support our commitment to reliable supply for the global research community.

Storage

Preserve in a tightly closed container, protected from light. Store at 2-8°C (refrigerated) or as indicated on the label or COA. This material is hygroscopic (moisture-sensitive) and light-sensitive; ensure containers are sealed under inert atmosphere if specified and kept in a cool, dry place.

Specification

Item	Specification
Appearance	Yellow to orange powder or crystalline solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.