Description

4,5,6,7-Tetrachloro-1,2-Dihydro-3H-Indol-3-One is a halogenated indole derivative, a versatile and high-value synthetic intermediate in advanced organic chemistry. Its unique polyhalogenated structure makes it a critical precursor for constructing complex molecules, particularly in the development of active pharmaceutical ingredients (APIs) and specialty agrochemicals. This compound is essential for research and production chemists in the pharmaceutical, agrochemical, and fine chemical industries seeking to introduce specific chlorinated indole scaffolds into their target molecules.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and other therapeutic areas.
• Agrochemical Synthesis: Serves as a precursor in the development of advanced herbicides, fungicides, and insecticides with specific modes of action.
• Material Science Research: Used in the creation of organic electronic materials and dyes due to its electron-deficient aromatic system.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying enzyme function and biological pathways.
• Complex Natural Product Analog Synthesis: Facilitates the laboratory synthesis of analogs to naturally occurring indole alkaloids for structure-activity relationship (SAR) studies.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving global clients.

Basic Information

Product Name	4,5,6,7-Tetrachloro-1,2-Dihydro-3H-Indol-3-One
CAS No.	73384-98-2
Molecular Formula	C8H3Cl4NO
Molecular Weight	284.93 g/mol
Synonyms	3H-Indol-3-one, 4,5,6,7-tetrachloro-1,2-dihydro-; 4,5,6,7-Tetrachloroindolin-3-one; 4,5,6,7-Tetrachloro-2,3-dihydro-1H-indol-3-one; Tetrachloroindolinone; 1,2-Dihydro-4,5,6,7-tetrachloro-3H-indol-3-one; 73384-98-2; NSC 407303
EINECS	Contact for details

Quality Control

Every batch of 4,5,6,7-Tetrachloro-1,2-Dihydro-3H-Indol-3-One is manufactured under strict quality management systems. Our products undergo rigorous quality testing, including HPLC for purity and identity confirmation, to ensure compliance with industry standards and customer-specific requirements. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is available for each lot and provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong bases and oxidizing agents. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.