Description

1,10-Decanedioic-D16 Acid is a deuterium-labeled analog of sebacic acid, where all sixteen hydrogen atoms are replaced by the stable isotope deuterium. This high isotopic purity makes it an indispensable internal standard and tracer in quantitative mass spectrometry and metabolic research. It is primarily utilized by analytical laboratories, pharmaceutical R&D departments, and academic institutions engaged in advanced material science and pharmacokinetic studies.

Application

• Internal Standard for Mass Spectrometry (MS): Essential for accurate quantification of sebacic acid and related dicarboxylic acids in complex biological matrices like plasma, urine, and tissue samples.
• Metabolic Pathway Tracing: Used in stable isotope labeling studies to elucidate metabolic fluxes and degradation pathways in biochemical and pharmacological research.
• Pharmaceutical Impurity Profiling: Serves as a reference standard in the development and validation of analytical methods for drug substances and their impurities.
• Polymer Science Research: Acts as a labeled monomer for studying polymerization mechanisms, kinetics, and the properties of resulting polymers, such as nylons and polyesters.
• Environmental Analysis: Employed as a tracer in environmental fate studies to monitor the degradation and movement of sebacic acid derivatives.
• Nuclear Magnetic Resonance (NMR) Spectroscopy: Useful as a deuterated solvent or shift reference in specific NMR applications.

Basic Information

Product Name	1,10-Decanedioic-D16 Acid
CAS No.	73351-71-0
Molecular Formula	C₁₀D₁₆O₄
Molecular Weight	216.32 g/mol
Synonyms	Sebacic Acid-D16; Decanedioic-1,2,3,4,5,6,7,8,9,10,11,12,13,14,15,16-D16 Acid; Deuterated Sebacic Acid; Perdeuterated Sebacic Acid; 1,10-Dideuteriooctadecanedioic Acid (fully deuterated); D16-Sebacic Acid; [D16]-Sebacic Acid; Octadecanedioic-1,2,3,4,5,6,7,8,9,10,11,12,13,14,15,16-D16 Acid
EINECS	Contact for details

Quality Control

Every batch of 1,10-Decanedioic-D16 Acid is produced and tested under strict quality management protocols to ensure exceptional isotopic and chemical purity for research applications. Our standard quality commitment includes comprehensive analysis via NMR, HPLC, and MS to confirm deuterium incorporation and chemical identity. A Certificate of Analysis (COA) detailing batch-specific results for isotopic purity, chemical purity, and other critical parameters is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after use to prevent moisture absorption, which can affect stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (MS)	Conforms to structure
Isotopic Purity (D-content)	≥ 98 atom % D
Chemical Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.