Description

1H-Pyrazole, 1-Acetyl-3,5-Difluoro- (9Ci) is a specialized fluorinated pyrazole derivative, a high-value intermediate in advanced organic synthesis. Its core value proposition lies in its unique molecular scaffold, which is critical for introducing the 1-acetyl-3,5-difluoropyrazole moiety into complex target molecules. This compound is essential for research and development chemists and process engineers working in the pharmaceutical and agrochemical sectors, where it serves as a key building block for creating novel active ingredients.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, inflammation, and metabolic diseases.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides, fungicides, and insecticides, leveraging the bioactivity of the fluorinated pyrazole core.
• Material Science Research: Serves as a precursor for developing advanced organic materials, including liquid crystals and functional polymers with specific electronic properties.
• Chemical Biology Probe Development: Employed in the design and synthesis of molecular probes for studying enzyme mechanisms and protein-ligand interactions.
• Custom Synthesis & Contract Manufacturing: A key starting material for custom synthesis projects and scale-up processes under cGMP or ISO standards for client-specific molecules.

Basic Information

Product Name	1H-Pyrazole, 1-Acetyl-3,5-Difluoro- (9Ci)
CAS No.	73311-18-9
Molecular Formula	C5H4F2N2O
Molecular Weight	146.10 g/mol
Synonyms	1-Acetyl-3,5-difluoropyrazole; 3,5-Difluoro-1H-pyrazole-1-acetic acid (related); 3,5-Difluoropyrazole-1-acetic acid (related); 1-Acetyl-3,5-difluoro-1H-pyrazole; 73311-18-9; 1-Acetyl-3,5-difluoropyrazole (9CI); 1-(3,5-Difluoropyrazol-1-yl)ethanone
EINECS	Contact for details

Quality Control

Our 1-Acetyl-3,5-difluoropyrazole is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment supports applications requiring high-purity intermediates for research and cGMP-compliant production.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.