Description

1-(6,7-Dichloroisoquinolin-2(1H)-Yl)Ethan-1-One is a high-purity, heterocyclic organic compound featuring a dichlorinated isoquinoline core, serving as a critical advanced pharmaceutical intermediate. This compound matters for its role in the synthesis of complex molecules, particularly in medicinal chemistry for developing new therapeutic agents. It is primarily needed by research institutions and pharmaceutical companies engaged in drug discovery, process development, and the manufacture of active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, oncology, and inflammation.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization processes to develop new chemical entities with improved efficacy and safety profiles.
• Process Chemistry & Scale-up: Employed in the development and optimization of scalable synthetic routes for Active Pharmaceutical Ingredients (APIs) under cGMP conditions.
• Agrochemical Research: Potential intermediate in the development of new pesticides or herbicides, leveraging its heterocyclic structure for biological activity.
• Organic Synthesis Reagent: Serves as a versatile precursor for further functionalization, enabling the creation of diverse chemical libraries for high-throughput screening.

Basic Information

Item	Detail
Product Name	1-(6,7-Dichloroisoquinolin-2(1H)-Yl)Ethan-1-One
CAS No.	73261-86-6
Molecular Formula	C11H7Cl2NO
Molecular Weight	240.09 g/mol
Synonyms	1-(6,7-Dichloro-1,2-dihydroisoquinolin-2-yl)ethanone; 2-Acetyl-6,7-dichloro-1,2-dihydroisoquinoline; 6,7-Dichloro-2-acetyl-1,2-dihydroisoquinoline; Ethanone, 1-(6,7-dichloro-1,2-dihydro-2-isoquinolinyl)-; 1-(6,7-Dichloro-1,2-dihydroisoquinolin-2-yl)ethan-1-one
EINECS	Contact for details

Quality Control

Our 1-(6,7-Dichloroisoquinolin-2(1H)-Yl)Ethan-1-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production can adhere to cGMP guidelines for pharmaceutical applications upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong oxidizing agents. For long-term storage, consider storing under an inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.