Description

2-Trimethylsilyl-n-tert-Butylacetaldimine is a specialized organosilicon reagent featuring a protected imine functional group, making it a valuable synthon for advanced organic synthesis. Its primary value lies in its role as a versatile building block for introducing nitrogen-containing moieties under controlled conditions, particularly in the synthesis of complex pharmaceuticals and fine chemicals. This compound is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors who require high-purity, reactive intermediates for constructing novel molecular architectures.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for introducing chiral amine centers.
• Asymmetric Synthesis: Serves as a precursor to chiral auxiliaries or ligands used in catalytic asymmetric reactions.
• Nucleophilic Amination Reagent: Used in the preparation of various amines and nitrogen heterocycles through imine chemistry.
• Organometallic Chemistry: Acts as a ligand or a precursor for ligands in transition metal catalysis.
• Agrochemical Synthesis: Intermediate in the production of herbicides, fungicides, and insecticides containing nitrogen-based functional groups.
• Material Science Research: Used in the development of novel silicon-nitrogen polymers or hybrid materials.
• Academic & Industrial R&D: A critical reagent for methodological development in organic synthesis and new reaction discovery.

Basic Information

Product Name	2-Trimethylsilyl-n-tert-Butylacetaldimine
CAS No.	73198-78-4
Molecular Formula	C9H21NSi
Molecular Weight	171.36 g/mol
Synonyms	N-(tert-Butyl)-1-(trimethylsilyl)ethanimine; 1-(Trimethylsilyl)-N-(tert-butyl)ethanimine; N-tert-Butyl-1-trimethylsilylethanimine; (E)-N-(tert-Butyl)-1-(trimethylsilyl)ethan-1-imine; 2-Trimethylsilyl-N-tert-butylacetaldimine; TMS-tert-Butylacetaldimine; Acetaldehyde N-tert-butylimine trimethylsilyl enol ether; Silicon-protected tert-butyl imine
EINECS	Contact for details

Quality Control

Our 2-Trimethylsilyl-n-tert-Butylacetaldimine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including GC, NMR, and Karl Fischer titration, to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment ensures the material meets the stringent requirements for research and process development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (argon or nitrogen) to prevent moisture ingress and decomposition. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.