Description

2-(2-((tert-Butoxycarbonyl)Amino)Thiazol-4-Yl)-2-Oxoaceticacid is a high-purity, advanced pharmaceutical intermediate featuring a protected amino-thiazole scaffold. This compound is critical for the synthesis of complex molecules, offering a versatile building block for medicinal chemistry research and development. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical and biotechnology industries for creating novel active pharmaceutical ingredients (APIs) and drug candidates.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of complex drug molecules, particularly those containing thiazole heterocycles.
• Protease Inhibitor Research: Used in the development of protease inhibitors, leveraging its reactive oxoacetic acid moiety.
• Antibiotic & Antiviral Agent Synthesis: Serves as a precursor in the creation of novel antibiotics and antiviral compounds.
• Peptidomimetics Development: Integral for constructing peptidomimetic scaffolds in drug discovery programs.
• Chemical Biology Probes: Employed in the design and synthesis of chemical probes for target identification and validation.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs and research institutions for custom synthesis projects and scale-up activities.

Basic Information

Product Name	2-(2-((tert-Butoxycarbonyl)Amino)Thiazol-4-Yl)-2-Oxoaceticacid
CAS No.	73181-56-3
Molecular Formula	C₁₀H₁₂N₂O₅S
Molecular Weight	272.28 g/mol
Synonyms	2-(2-((tert-Butoxycarbonyl)amino)-1,3-thiazol-4-yl)-2-oxoacetic acid; 2-[2-[(tert-Butoxycarbonyl)amino]-1,3-thiazol-4-yl]-2-oxoacetic Acid; Boc-Amino-Thiazole-Oxoacetic Acid; 2-Oxo-2-[2-[[(2-methylpropan-2-yl)oxycarbonyl]amino]-1,3-thiazol-4-yl]acetic acid; (Boc-Amino-Thiazol-4-yl)-Oxoacetic Acid; 4-(Boc-amino)-2-thiazoleglyoxylic acid; 73181-56-3; tert-Butyl N-[4-(oxoacetyl)-1,3-thiazol-2-yl]carbamate
EINECS	Contact for details

Quality Control

Our 2-(2-((tert-Butoxycarbonyl)Amino)Thiazol-4-Yl)-2-Oxoaceticacid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the high standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider storing under an inert atmosphere such as nitrogen or argon.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.