Description

5-Fluoroindole-3-Acetonitrile is a versatile fluorinated indole derivative, a key building block in advanced organic synthesis. Its value lies in its reactive nitrile group and indole scaffold, enabling the construction of complex molecules with high precision. This intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing novel active compounds.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of fluorinated drug candidates, including kinase inhibitors, serotonin receptor modulators, and other biologically active molecules.
• Agrochemical Research: Used in the development of new-generation herbicides, fungicides, and plant growth regulators that leverage the fluorine atom for enhanced efficacy and stability.
• Organic Synthesis Building Block: Serves as a versatile starting material for constructing complex heterocyclic compounds and fine chemicals via reactions at the nitrile and indole positions.
• Material Science Research: Employed in the development of specialty chemicals, dyes, and functional materials where the indole fluorophore is of interest.

Basic Information

Product Name	5-Fluoroindole-3-Acetonitrile
CAS No.	73139-85-2
Molecular Formula	C₁₀H₇FN₂
Molecular Weight	174.18 g/mol
Synonyms	5-Fluoro-1H-indole-3-acetonitrile; (5-Fluoro-1H-indol-3-yl)acetonitrile; 3-(Cyanomethyl)-5-fluoroindole; 5-Fluoroindole-3-glycolonitrile; 5-Fluoro-3-indoleacetonitrile; 2-(5-Fluoro-1H-indol-3-yl)acetonitrile; 5-Fluoroindolyl-3-acetonitrile
EINECS	Contact for details

Quality Control

Our 5-Fluoroindole-3-Acetonitrile is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for research and development. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.